Assessment of Vaccine Hesitancy to a COVID-19 Vaccine in Cameroonian Adults and Its Global Implication.

Assessment of Vaccine Hesitancy to a COVID-19 Vaccine in Cameroonian Adults and Its Global Implication.
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DOI:
10.3390/vaccines9020175
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发表时间:
2021-02-19
期刊:
影响因子:
7.8
通讯作者:
Titanji VPK
Titanji VPK
中科院分区:
医学3区
文献类型:
--
作者:
Dinga JN;Sinda LK;Titanji VPK

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自2019年12月2019冠状病毒病暴发以来,尚未开发出全球共识的治疗方法,并被普遍接受。然而,根除这种疾病需要一种安全有效的疫苗。为了为最终研制出安全有效的COVID-19疫苗做好准备并加强其吸收率,必须评估喀麦隆人对疫苗的犹豫态度。在获得布埃亚大学机构审查委员会的伦理许可后,(2020年5月至8月)对在线或亲自同意的成年人进行了问卷调查。定性专题分析是为了分析参与者对开放性问题的回答。采用了演绎方法,即根据世界卫生组织(世卫组织)战略咨询专家组(SAGE)工作组疫苗犹豫决定因素矩阵的代码和模式。完成问卷调查的喀麦隆成年人的同意人数为2512(两千五百一十二)。喀麦隆人对COVID-19疫苗的犹豫率为84.6%。使用世卫组织推荐的疫苗犹豫决定因素矩阵,本研究中观察到的最突出的决定因素是:传播和媒体环境、对制药业的看法、疫苗的可靠性和/或来源以及成本。大多数喀麦隆人同意,尽管临床试验有好处,但他们更希望临床试验在非洲大陆之外进行,并让非洲科学家参与,以便最终被接受和吸收。如果要在非洲或喀麦隆成功接种COVID-19疫苗,就必须通过公众参与方法解决安全性、有效性和信心问题。由于本研究是按照世卫组织标准进行的,因此其结果可以与在不同文化环境中使用类似标准进行的其他研究进行比较。
Since the outbreak of COVID-19 in December 2019, no global consensus treatment has been developed and generally accepted for the disease. However, eradicating the disease will require a safe and efficacious vaccine. In order to prepare for the eventual development of a safe and efficacious COVID-19 vaccine and to enhance its uptake, it is imperative to assess vaccine hesitancy in Cameroonians. After obtaining ethical clearance from the Institutional Review Board of the University of Buea, a questionnaire was administered (May–August 2020) to consenting adults either online or in person. A qualitative thematic analysis was done to analyze the participants’ answers to the open questions. A deductive approach was used, that is, the codes and patterns according to the World Health Organization (WHO) Strategic Advisory Group of Experts (SAGE) Working Group Matrix of Determinants of vaccine hesitancy. The number of consenting adult Cameroonians who completed the questionnaire were 2512 (Two thousand five hundred and twelve). Vaccine hesitancy to a COVID-19 vaccine was 84.6% in Cameroonians. Using the WHO recommended Matrix of Determinant of Vaccine hesitancy, the most prominent determinants observed in this study were: Communication and Media Environment, Perception of pharmaceutical industry, Reliability and/or source of vaccine and cost. Most Cameroonians agree that even though there are benefits of a clinical trial, they will prefer it should be done out of the continent and involving African scientists for eventual acceptance and uptake. The concerns of safety, efficacy and confidence has to be addressed using a Public Engagement approach if a COVID-19 vaccine has to be administered successfully in Africa or Cameroon specifically. Since this study was carried out following WHO standards, its result can be compared to those of other studies carried out in different cultural settings using similar standards.
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发表时间: 2019-06-01
期刊: MEDICINA-LITHUANIA
影响因子: 2.6
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发表时间: 2015-10-01
期刊: The Clinical journal of pain
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DOI: 10.1016/j.vaccine.2012.02.025
发表时间: 2012-05-28
期刊: VACCINE
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