Real-time magnetic resonance imaging-guided radiofrequency atrial ablation and visualization of lesion formation at 3 Tesla.
Real-time magnetic resonance imaging-guided radiofrequency atrial ablation and visualization of lesion formation at 3 Tesla.
复制标题
DOI：
10.1016/j.hrthm.2010.10.032
复制
发表时间：
2011-02
期刊：
影响因子：
5.5
通讯作者：
Marrouche NF
中科院分区：
文献类型：
--
作者：
Vergara GR;Vijayakumar S;Kholmovski EG;Blauer JJ;Guttman MA;Gloschat C;Payne G;Vij K;Akoum NW;Daccarett M;McGann CJ;Macleod RS;Marrouche NF
MRI允许可视化射频消融损伤的位置和范围、心肌瘢痕形成以及损伤形成的实时（RT）评估。在这项研究中，我们报告了一种新的基于3特斯拉RT-MRI的猪射频消融模型和射频能量输送过程中心房内病变形成的可视化。开发基于3 T RT-MRI的导管消融和病变可视化系统。在RT-MRI引导下向6只猪输送射频能量。使用了一种新型MRI兼容标测和消融导管。在RT-MRI下，该导管被安全引导并定位在左心房或右心房内。记录单极和双极电描记图。使用T1加权梯度回波序列可视化导管头端-组织界面。然后以功率控制方式输送射频能量。消融过程中采用T2加权（T2 w）HASTE序列观察心肌变化和病变形成。在30%的消融中实现了病变形成的实时可视化。在其他病例中，病变形成于成像区域外（25%）或未形成病变（45%），可能是由于组织-导管头端接触不良。通过晚期钆增强（LGE）MRI和肉眼组织检查证实了病变的存在。MRI兼容导管可在3 T RT-MRI引导下导航并安全输送射频能量。在RT成像期间记录电描记图也是可行的。在射频能量输送过程中形成的病变可以实时可视化，并使用T2 w HASTE成像进行了证明。
MRI allows visualization of location and extent of RF ablation lesion, myocardial scar formation, and real-time (RT) assessment of lesion formation. In this study, we report a novel 3-Tesla RT-MRI based porcine RF ablation model and visualization of lesion formation in the atrium during RF energy delivery. To develop of a 3-Tesla RT-MRI based catheter ablation and lesion visualization system. RF energy was delivered to six pigs under RT-MRI guidance. A novel MRI compatible mapping and ablation catheter was used. Under RT-MRI this catheter was safely guided and positioned within either the left or right atrium. Unipolar and bi-polar electrograms were recorded. The catheter tip-tissue interface was visualized with a T1-weighted gradient echo sequence. RF energy was then delivered in a power-controlled fashion. Myocardial changes and lesion formation were visualized with a T2-weighted (T2w) HASTE sequence during ablation. Real-time visualization of lesion formation was achieved in 30% of the ablations performed. In the other cases, either the lesion was formed outside the imaged region (25%) or lesion was not created (45%) presumably due to poor tissue-catheter tip contact. The presence of lesions was confirmed by late gadolinium enhancement (LGE) MRI and macroscopic tissue examination. MRI compatible catheters can be navigated and RF energy safely delivered under 3-Tesla RT-MRI guidance. It is also feasible to record electrograms during RT imaging. Real-time visualization of lesion as it forms during delivery of RF energy is possible and was demonstrated using T2w HASTE imaging.
登录
查看更多内容
影响因子：
8.4
作者：
Schmidt, Ehud J.;Mallozzi, Richard P.;Reddy, Vivek Y.
通讯作者：
Reddy, Vivek Y.
影响因子：
5.5
作者：
Dickfeld, Timm;Kato, Ritsushi;Halperin, Henry
通讯作者：
Halperin, Henry
DOI：
10.1253/jcj.42.313
发表时间：
1978-01-01
期刊：
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION
影响因子：
--
作者：
MITSUI, T;IJIMA, H;HORI, M
通讯作者：
HORI, M
影响因子：
37.8
作者：
Lardo, AC;McVeigh, ER;Halperin, HR
通讯作者：
Halperin, HR
影响因子：
19.7
作者：
Peters, Dana C.;Wylie, John V.;Manning, Warren J.
通讯作者：
Manning, Warren J.