Prevalence of Vitamin D and Calcium Deficiency and Insufficiency in Women of Childbearing Age and Associated Risk Factors: A Systematic Review and Meta-Analysis.
Prevalence of Vitamin D and Calcium Deficiency and Insufficiency in Women of Childbearing Age and Associated Risk Factors: A Systematic Review and Meta-Analysis.
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DOI：
10.3390/nu14204351
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发表时间：
2022-10-17
期刊：
影响因子：
5.9
通讯作者：
Oliveira C
中科院分区：
文献类型：
--
作者：
da Silveira EA;Moura LANE;Castro MCR;Kac G;Hadler MCCM;Noll PRES;Noll M;Rezende ATO;Delpino FM;Oliveira C
维生素D缺乏和不足以及血清钙水平低可引发育龄妇女的不良健康后果。因此，我们的目的是估计巴西育龄妇女血清维生素D和钙缺乏症的患病率和相关的危险因素，并评估是否有根据国家的地区和怀孕与否的患病率的差异。使用以下数据库进行系统性文献综述：PubMed、LILACS、Embase、Scopus和Web of Science。纳入了横断面、队列和干预研究。在孕妇中，维生素D缺乏的患病率为0%至27%，维生素D不足的患病率为33.9%至70.4%。在未怀孕妇女中，维生素D缺乏的患病率为0%至41.7%，维生素D不足的患病率为38.5%至69.3%。我们发现育龄妇女维生素D缺乏和不足的患病率很高，其中一半以上的妇女维生素D不足。据观察，南部地区维生素D缺乏和不足的流行率最高。无法评估与缺钙相关的患病率和因素。
Vitamin D deficiency and insufficiency as well as low serum calcium levels can trigger negative health outcomes in women of childbearing age. Therefore, we aimed to estimate the prevalence of serum vitamin D and calcium deficiencies and insufficiencies and associated risk factors in Brazilian women of childbearing age and to assess whether there are differences in prevalence according to regions of the country and the presence or absence of pregnancy. The systematic literature review was performed using the following databases: PubMed, LILACS, Embase, Scopus, and Web of Science. Cross-sectional, cohort, and intervention studies were included. Among pregnant women, the prevalence of vitamin D deficiency ranged from 0% to 27% and of vitamin D insufficiency from 33.9% to 70.4%. Among non-pregnant women, the prevalence of vitamin D deficiency ranged from 0% to 41.7% and of vitamin D insufficiency from 38.5% to 69.3%. We found a high prevalence of vitamin D deficiency and insufficiency in women of childbearing age, with insufficiency affecting more than half of these women. The highest prevalence of vitamin D deficiency and insufficiency was observed in the South region. It was not possible to assess the prevalence and factors associated with calcium deficiency.
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