Evidence that the Lub blood group antigen is located on red cell membrane glycoproteins of 85 and 78 kd

Evidence that the Lub blood group antigen is located on red cell membrane glycoproteins of 85 and 78 kd
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Lub 血型抗原位于 85 和 78 kd 红细胞膜糖蛋白上的证据

DOI:
10.1046/j.1537-2995.1987.27187121477.x
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发表时间:
1987
期刊:
影响因子:
2.9
通讯作者:
G. Daniels
G. Daniels
中科院分区:
医学3区
文献类型:
--
作者:
S. Parsons;G. Mallinson;P. Judson;D. Anstee;M. Tanner;G. Daniels

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制备了一种特异性抗Lub的鼠源性单抗。用该单抗对Lu(b+)红细胞膜的电泳组分进行免疫印迹,鉴定出两种相对分子质量分别为85和78kd的糖蛋白。这些糖蛋白组分上Lub抗原活性的表达取决于一个或多个N-糖苷键连接的寡糖的存在和二硫键的存在。
A murine monoclonal antibody of specificity anti‐Lub was produced. Immunoblotting of the electrophoretically separated components of membranes from Lu(b+) red cells with the monoclonal antibody identified two glycoproteins of relative molecular mass 85 and 78 kd, respectively. The expression of Lub antigenic activity on these glycoprotein components was shown to be dependent on the presence of one or more N‐glycosidically linked oligosaccharides and on the presence of disulphide bonding.
DOI: 10.1073/pnas.79.15.4540
发表时间: 1982-01-01
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子: --
作者:
ELDER, JH;ALEXANDER, S
通讯作者: ALEXANDER, S
DOI: --
发表时间: 1984
期刊: Blood
影响因子: 20.3
作者:
Telen,MJ;Palker,TJ;Haynes,BF
通讯作者: Haynes,BF