Neighborhood Environment and Cognition in Older Adults: A Systematic Review.

Neighborhood Environment and Cognition in Older Adults: A Systematic Review.
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DOI:
10.1016/j.amepre.2017.02.013
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发表时间:
2017-08
影响因子:
5.5
通讯作者:
Rodriguez DA
Rodriguez DA
中科院分区:
医学2区
文献类型:
--
作者:
Besser LM;McDonald NC;Song Y;Kukull WA;Rodriguez DA

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一些证据表明,治疗血管危险因素和进行精神刺激活动可能会延迟老年人的认知障碍发作。暴露在复杂的邻里环境中可能是帮助延缓认知能力下降的一种机制。对PubMed、Web of Science和ProQuest Dissertation and Theses Global数据库进行了系统综述,确定了1989年2月1日至2016年3月5日发表的25项研究(数据合成,2015年5月3日至2016年10月7日)。该综述仅限于定量研究,重点关注:(1)社区社会和建筑环境和认知;(2)年龄≥45岁的社区居民。大多数研究是横断面的,美国-并发现至少有一个重要的关联。在许多情况下,措施和邻域定义的多样性限制了调查结果的综合。证据是适度强的邻里SES和认知之间的关联和适度的邻里人口统计,设计,目的地可达性和认知之间的关联。大多数研究效果修改发现显着的协会,与一些证据的效果修改的社区SES认知协会的个人层面的SES。没有一项研究的偏倚风险较低,许多研究测试了多种关联,增加了统计学显著性发现的机会。考虑到迄今为止的研究,邻里特征和认知之间的关联的证据是适度的。未来的研究应包括纵向措施的邻里特点和认知,检查潜在的影响修饰符,如性别和残疾,和研究介质,可能有助于阐明的生物机制,邻里环境和认知。
Some evidence suggests that treating vascular risk factors and performing mentally stimulating activities may delay cognitive impairment onset in older adults. Exposure to a complex neighborhood environment may be one mechanism to help delay cognitive decline. PubMed, Web of Science, and ProQuest Dissertation and Theses Global database were systematically reviewed, identifying 25 studies published from February 1, 1989 to March 5, 2016 (data synthesized, May 3, 2015–October 7, 2016). The review restricted to quantitative studies focused on: (1) neighborhood social and built environment and cognition; and (2) community-dwelling adults aged ≥45 years. The majority of studies were cross-sectional, U.S.-based, and found at least one significant association. The diversity of measures and neighborhood definitions limited the synthesis of findings in many instances. Evidence was moderately strong for an association between neighborhood SES and cognition and modest for associations between neighborhood demographics, design, and destination accessibility and cognition. Most studies examining effect modification found significant associations, with some evidence for effect modification of the neighborhood SES–cognition association by individual-level SES. No studies had low risk of bias and many tested multiple associations that increased the chance of a statistically significant finding. Considering the studies to date, the evidence for an association between neighborhood characteristics and cognition is modest. Future studies should include longitudinal measures of neighborhood characteristics and cognition, examine potential effect modifiers such as sex and disability, and study mediators that may help elucidate the biological mechanisms linking neighborhood environment and cognition.
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