Characterization of a periplasmic protein involved in iron utilization of Actinobacillus actinomycetemcomitans
Characterization of a periplasmic protein involved in iron utilization of Actinobacillus actinomycetemcomitans
复制标题
伴随放线放线杆菌铁利用的周质蛋白的表征
作者：
Peter T. J. Willemsen;Irma Vulto;Mike Boxem;Johannes;De;Graaff
牙周病细菌伴放线放线杆菌具有35 kDa的周质铁抑制蛋白。其调节由Fur蛋白介导，如从35-kDa蛋白基因的-35位的Fur结合共有序列和从具有改变的Fur结合序列的突变体中基因的松弛表达推断的。35 kDa的蛋白质，命名为AfuA，具有很强的同源性，分别作为周质铁转运蛋白的流感嗜血杆菌和脑膜炎奈瑟氏球菌的HitA和FbpA。
The periodontopathic bacterium Actinobacillus actinomycetemcomitans possesses a 35-kDa periplasmic iron-repressible protein. Its regulation is mediated by the Fur protein, as was inferred from the Fur-binding consensus sequence at the -35 position of the gene for the 35-kDa protein and from the relaxed expression of the gene in a mutant with an altered Fur-binding sequence. The 35-kDa protein, designated AfuA, has strong homology to HitA and FbpA of Haemophilus influenzae and Neisseria meningitidis, respectively, which serve as periplasmic iron transport proteins.
影响因子：
--
作者：
Genco,RJ;Zambon,JJ;Christersson,LA
通讯作者：
Christersson,LA