Trends in bacterial and fungal keratitis in South India, 2002-2012.
Trends in bacterial and fungal keratitis in South India, 2002-2012.
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DOI：
10.1136/bjophthalmol-2014-305000
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发表时间：
2015-03
期刊：
影响因子：
--
通讯作者：
Keenan JD
中科院分区：
文献类型：
--
作者：
Lalitha P;Prajna NV;Manoharan G;Srinivasan M;Mascarenhas J;Das M;D'Silva SS;Porco TC;Keenan JD
旨在评估从印度南部一家三级护理医疗中心感染性角膜炎患者的角膜刮片中鉴定出的微生物的趋势。我们回顾了 2002 年至 2012 年印度马杜赖 Aravind 眼科医院微生物实验室的记录。我们从培养和涂片结果中确定了所有角膜溃疡的微生物原因，并评估了细菌和真菌性角膜炎随时间变化的趋势。 2002年至2012年间，对23,897名角膜溃疡患者进行角膜涂片检查，结果发现真菌占34.3%，细菌占24.7%，细菌占38.3%。在此期间，每年因细菌引起的角膜炎病例数从677例减少到412例，每年因真菌引起的病例数从609例增加到863例。在对每年门诊总人数的分析中，细菌涂片阳性人数的下降具有统计学意义（P<0.001），但真菌阳性人数的增加并不显着（P=0.73）。在此期间，单个细菌或真菌生物体的相对频率保持相对稳定。在印度南部的一家三级眼保健中心，过去 11 年中涂阳细菌性角膜炎的数量有所减少。这种下降可能反映了印度的经济发展和抗生素获取的增加。
To assess the trends in microbiological organisms identified from corneal scrapings from patients with infectious keratitis at a tertiary care medical center in South India. We reviewed the records of the Microbiology Laboratory at Aravind Eye Hospital in Madurai, India from 2002 until 2012. We identified the microbiologic cause of all corneal ulcers from the culture and smear results, and assessed for trends in bacterial and fungal keratitis over time. Of 23,897 corneal ulcer patients with a corneal smear from 2002–2012, a fungal organism was identified in 34.3%, a bacterial organism in 24.7%, and no organism in 38.3%. During this period, the annual number of keratitis cases due to bacteria decreased from 677 to 412, and the annual number due to fungus increased from 609 to 863. In analyses accounting for the total number of outpatients seen each year, the decline in number of smears positive for bacteria was statistically significant (P<0.001) but the increase in the number positive for fungus was not (P=0.73). The relative frequency of individual bacterial or fungal organisms remained relatively stable over this time. At a tertiary eye care center in South India, there has been a reduction in the numbers of smear-positive bacterial keratitis over the past 11 years. This decline likely reflects economic development in India and increased access to antibiotics.
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DOI：
10.1136/bjo.2009.169607
发表时间：
2011-06
期刊：
The British journal of ophthalmology
影响因子：
--
作者：
Shah A;Sachdev A;Coggon D;Hossain P
通讯作者：
Hossain P
影响因子：
1.8
作者：
Sengupta, Sabyasachi;Thiruvengadakrishnan, Krishnan;Vaitilingam, Manivasagam C.
通讯作者：
Vaitilingam, Manivasagam C.
影响因子：
--
作者：
Prajna, Namperumalsamy V.;Mascarenhas, Jeena;Krishnan, Tiruvengada;Reddy, P. Ravindranath;Prajna, Lalitha;Srinivasan, Muthiah;Vaitilingam, C. M.;Hong, Kevin C.;Lee, Salena M.;McLeod, Stephen D.;Zegans, Michael E.;Porco, Travis C.;Lietman, Thomas M.;Acharya, Nisha R.
通讯作者：
Acharya, Nisha R.
影响因子：
0.3
作者：
Dhakhwa, K.;Sharma, M. K.;Rai, (K C) S.
通讯作者：
Rai, (K C) S.
影响因子：
2.1
作者：
Khanal, B;Deb, M;Sethi, HS
通讯作者：
Sethi, HS