Relationship between body mass index and prognosis of patients presenting with potential acute coronary syndromes.
Relationship between body mass index and prognosis of patients presenting with potential acute coronary syndromes.
复制标题
体重指数与潜在急性冠状动脉综合征的患者的预后之间的关系。
DOI：
10.1111/acem.12211
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发表时间：
2013-09
期刊：
影响因子：
--
通讯作者：
Hollander JE
中科院分区：
文献类型：
--
作者：
Dooley J;Chang AM;A Salhi R;Hollander JE
研究肥胖和急性冠状动脉综合征（ACS）之间关系的研究仅限于确诊的患者。作者试图确定潜在ACS急诊科（艾德）患者的体重指数（BMI）与30天心血管事件之间的关系。这是一项针对因潜在ACS就诊于艾德的患者的前瞻性队列研究的次要分析。患者根据其BMI分层：体重不足（BMI < 18.49 kg/m2）、正常体重（BMI = 18.5至24.99 kg/m2）、超重（BMI = 25至29.99 kg/m2）、肥胖（BMI = 30至34.99 kg/m2）和非常肥胖（BMI > 35 kg/m2）。主要转归为发病后30天内的急性心肌梗死（AMI）、死亡或血运重建。使用逻辑回归分析调整混杂变量，并列出心脏事件和再入院结局的调整比值比（aOR）和95%置信区间（CI）。在本研究纳入的3，946例患者中，73例（1.9%）体重不足，911例（23%）体重正常，1，199例（30.4%）超重，872例（22.1%）肥胖，891例（22.6%）非常肥胖。尽管肥胖程度的增加与更多的心脏病危险因素有关，但体重正常和体重不足者之间的30天心血管事件没有差异（aOR = 1.1; 95% CI = 0.4 - 2.7）、超重（aOR = 1.0; 95% CI = 0.7 - 1.4）、肥胖（aOR = 1.2; 95% CI = 0.8 - 1.7）或非常肥胖（aOR = 0.8; 95% CI = 0.5 - 1.3）。体重过轻的患者更有可能在30天内再次入院（aOR = 1.9; 95% CI = 1.0 - 3.7），而非常肥胖的患者在30天内再次入院的可能性较小（aOR = 0.7; 95% CI = 0.5 - 0.9）。在因潜在ACS而到艾德急诊室就诊的患者中，BMI与30天时心血管结局的高风险无关。
Studies examining the relationship between obesity and acute coronary syndrome (ACS) have been limited to patients with confirmed diagnoses. The authors sought to determine the relationship between body mass index (BMI) and 30-day cardiovascular events in emergency department (ED) patients with potential ACS. This was a secondary analysis of a prospective cohort study of patients who presented to the ED with potential ACS. Patients were stratified according to their BMI: underweight (BMI < 18.49 kg/m2), normal weight (BMI = 18.5 to 24.99 kg/m2), overweight (BMI = 25 to 29.99 kg/m2), obese (BMI = 30 to 34.99 kg/m2), and very obese (BMI > 35 kg/m2). The primary outcome was acute myocardial infarction (AMI), death, or revascularization within 30 days of presentation. A logistic regression analysis was used to adjust for confounding variables and adjusted odds ratios (aOR) with 95% confidence intervals (CIs) are presented for cardiac events and readmission outcomes. Of the 3,946 patients included in this study, 73 (1.9%) were underweight, 911 (23%) were normal weight, 1,199 (30.4%) were overweight, 872 (22.1%) were obese, and 891 (22.6%) were very obese. Although increased levels of obesity were associated with a greater number of cardiac risk factors, there was no difference in 30-day cardiovascular events between those of normal weight and underweight (aOR = 1.1; 95% CI = 0.4 to 2.7), overweight (aOR = 1.0; 95% CI = 0.7 to 1.4), obese (aOR = 1.2; 95% CI = 0.8 to1.7), or very obese (aOR = 0.8; 95% CI = 0.5 to 1.3). Those who were underweight were more likely to be readmitted within 30 days (aOR = 1.9; 95% CI = 1.0 to 3.7), and those who were very obese were less likely to be readmitted within 30 days (aOR = 0.7; 95% CI = 0.5 to 0.9). Among patients who present to the ED with potential ACS, BMI is not associated with higher risk of cardiovascular outcomes at 30 days.
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影响因子：
4.4
作者：
Hollander, JE;Valentine, SM;Brogan, GX
通讯作者：
Brogan, GX
影响因子：
37.8
作者：
Amsterdam, Ezra A.;Kirk, J. Douglas;Thompson, Paul D.
通讯作者：
Thompson, Paul D.
影响因子：
4.4
作者：
Chang, Anna Marie;Mumma, Bryn;Hollander, Judd E.
通讯作者：
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DOI：
10.1016/s0735-1097(02)01687-x
发表时间：
2002-03-06
影响因子：
24
作者：
Gurm, HS;Whitlow, PL;BARI Invest
通讯作者：
BARI Invest
影响因子：
3.5
作者：
Nigam, Anil;Wright, R. Scott;Jaffe, Allan S.
通讯作者：
Jaffe, Allan S.