Epidemiology of COVID-19 Outbreak on Cruise Ship Quarantined at Yokohama, Japan, February 2020.

Epidemiology of COVID-19 Outbreak on Cruise Ship Quarantined at Yokohama, Japan, February 2020.
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2020年2月,在日本横滨,在巡航船上的Covid-19爆发流行病学。

DOI:
10.3201/eid2611.201165
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发表时间:
2020-11
影响因子:
11.8
通讯作者:
Expert Taskforce for the COVID-19 Cruise Ship Outbreak
Expert Taskforce for the COVID-19 Cruise Ship Outbreak
中科院分区:
医学2区
文献类型:
--
作者:
Expert Taskforce for the COVID-19 Cruise Ship Outbreak

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为了加深对冠状病毒病 (COVID-19) 的了解,我们评估了 2020 年 2 月 5 日至 24 日一艘游轮上爆发的流行病学。研究人群包括 2 月 3 日的船上人员(2,666 名乘客,1,045 名船员)。乘客平均年龄为 66.1 岁,其中 55% 为女性;船员平均年龄为 36.6 岁,其中 81% 为男性。乘客中,544 人(20.4%)感染,314 人(57.7%)无症状。 4 人小屋的发病率最高(30.0%;n = 18)。船员中,143 人(13.7%)感染,64 人(44.8%)无症状。旅客病例在2月7日达到峰值,其中35人是在隔离前发病的。船员病例在2月11日至13日达到高峰。同一客舱内病例之间的中位连续间隔为2天。这项研究表明,严重急性呼吸综合征冠状病毒2在封闭环境中具有传染性,亚临床感染很常见,密切接触是传播的关键。
To improve understanding of coronavirus disease (COVID-19), we assessed the epidemiology of an outbreak on a cruise ship, February 5–24, 2020. The study population included persons on board on February 3 (2,666 passengers, 1,045 crew). Passengers had a mean age of 66.1 years and were 55% female; crew had a mean age of 36.6 years and were 81% male. Of passengers, 544 (20.4%) were infected, 314 (57.7%) asymptomatic. Attack rates were highest in 4-person cabins (30.0%; n = 18). Of crew, 143 (13.7%) were infected, 64 (44.8%) asymptomatic. Passenger cases peaked February 7, and 35 had onset before quarantine. Crew cases peaked on February 11 and 13. The median serial interval between cases in the same cabin was 2 days. This study shows that severe acute respiratory syndrome coronavirus 2 is infectious in closed settings, that subclinical infection is common, and that close contact is key for transmission.
DOI: 10.1056/nejmoa2001316
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