Anatomy of the female reproductive tract organs of the brown anole (Anolis sagrei).
Anatomy of the female reproductive tract organs of the brown anole (Anolis sagrei).
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棕色变色蜥（Anolis sagrei）雌性生殖道器官的解剖。
DOI：
10.1002/ar.25293
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发表时间：
2024
期刊：
影响因子：
--
通讯作者：
Behringer,RichardR
中科院分区：
文献类型：
--
作者：
Kircher,BonnieK;Stanley,EdwardL;Behringer,RichardR
有鳞爬行动物（蜥蜴和蛇）的雌性生殖是高度多样化的，生殖方式，窝卵数和生殖道形态在这组约11，000个物种中变化很大。最近，CRISPR基因组编辑技术需要对女性生殖解剖结构进行操作，这使得对这种解剖结构的更完整理解变得至关重要。本文描述了模式爬行动物棕色变色龙（Anolis sagrei）的成年雌性生殖解剖。我们发现，棕色变色龙雌性生殖道有三个不同的前后区域，漏斗，腺子宫和非腺子宫。漏斗有一个高度纤毛的上皮唇，在这个区域上皮是倒置的，因此纤毛存在于管的内侧和外侧。腺子宫有上皮导管和腺泡结构，上皮导管有管腔，腺泡结构有管腔。非腺性子宫从前到后形态不均匀，高度折叠的纤毛上皮转变为复层鳞状上皮。这种转变伴随着角蛋白-8表达的丧失，这些变化与哺乳动物宫颈中发生的形态学和基因表达变化相似。我们建议对非腺子宫的描述应包括“宫颈”和“阴道”的局部亚规范，因为这一术语变化更准确地描述了形态学。我们的数据扩展了爬行动物生殖器官形态的组织学研究，并扩大了我们对有鳞目动物和脊椎动物生殖系统解剖学变化的理解。
Female reproduction in squamate reptiles (lizards and snakes) is highly diverse and mode of reproduction, clutch size, and reproductive tract morphology all vary widely across this group of ~11,000 species. Recently, CRISPR genome editing techniques that require manipulation of the female reproductive anatomy have been developed in this group, making a more complete understanding of this anatomy essential. We describe the adult female reproductive anatomy of the model reptile the brown anole (Anolis sagrei). We show that the brown anole female reproductive tract has three distinct anterior‐to‐posterior regions, the infundibulum, the glandular uterus, and the nonglandular uterus. The infundibulum has a highly ciliated epithelial lip, a region where the epithelium is inverted so that cilia are present on the inside and outside of the tube. The glandular uterus has epithelial ducts that are patent with a lumen as well as acinar structures with a lumen. The nonglandular uterus has a heterogeneous morphology from anterior to posterior, with a highly folded, ciliated epithelium transitioning to a stratified squamous epithelium. This transition is accompanied by a loss of keratin‐8 expression and together, these changes are similar to the morphological and gene expression changes that occur in the mammalian cervix. We recommend that description of the nonglandular uterus include the regional sub‐specification of a “cervix” and “vagina” as this terminology change more accurately describes the morphology. Our data extend histological studies of reproductive organ morphology in reptiles and expand our understanding of the variation in reproductive system anatomy across squamates and vertebrates.
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影响因子：
1.5
作者：
S. M. Adams;S. Lui;S. M. Jones;M. Thompson;C. Murphy
通讯作者：
S. M. Adams;S. Lui;S. M. Jones;M. Thompson;C. Murphy
DOI：
10.1002/ar.21052
发表时间：
2010-05-01
影响因子：
2
作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
Richtsmeier, Joan T.
影响因子：
1.2
作者：
Besnard, V;Wert, SE;Whitsett, JA
通讯作者：
Whitsett, JA
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影响因子：
2.6
作者：
W. Fox;H. Dessauer
通讯作者：
H. Dessauer