Bacteriocins Targeting Gram-Negative Phytopathogenic Bacteria: Plantibiotics of the Future.
Bacteriocins Targeting Gram-Negative Phytopathogenic Bacteria: Plantibiotics of the Future.
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DOI：
10.3389/fmicb.2020.575981
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发表时间：
2020
影响因子：
5.2
通讯作者：
Walker D
中科院分区：
文献类型：
--
作者：
Rooney WM;Chai R;Milner JJ;Walker D
革兰氏阴性植物病原菌对粮食作物构成重大威胁。这些微生物入侵者导致了大量的植物疾病，并可能造成番茄、辣椒、土豆、橄榄和水稻等作物的毁灭性损失。目前减轻产量损失的疾病管理战略涉及使用往往对人类健康和环境都有害的化学品。细菌素是一种小的蛋白质类抗生素，由细菌产生，用来杀死密切相关的细菌，从而在一个利基内建立优势。当在野外使用时，它们可能代表着一种比化学品更安全的替代品。细菌素通常对其靶标表现出高度的选择性，没有靶外效应。本文综述了抗革兰氏阴性植物病原菌细菌素的研究现状。此外，我们将研究将细菌素武器化用于治疗细菌性植物疾病的可行性。
Gram-negative phytopathogenic bacteria are a significant threat to food crops. These microbial invaders are responsible for a plethora of plant diseases and can be responsible for devastating losses in crops such as tomatoes, peppers, potatoes, olives, and rice. Current disease management strategies to mitigate yield losses involve the application of chemicals which are often harmful to both human health and the environment. Bacteriocins are small proteinaceous antibiotics produced by bacteria to kill closely related bacteria and thereby establish dominance within a niche. They potentially represent a safer alternative to chemicals when used in the field. Bacteriocins typically show a high degree of selectivity toward their targets with no off-target effects. This review outlines the current state of research on bacteriocins active against Gram-negative phytopathogenic bacteria. Furthermore, we will examine the feasibility of weaponizing bacteriocins for use as a treatment for bacterial plant diseases.
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影响因子：
4.2
作者：
Chan YC;Wu HP;Chuang DY
通讯作者：
Chuang DY
影响因子：
3.3
作者：
Ghequire, Maarten G. K.;Li, Wen;De Mot, Rene
通讯作者：
De Mot, Rene
影响因子：
4.8
作者：
Grinter, Rhys;Roszak, Aleksander W.;Walker, Daniel
通讯作者：
Walker, Daniel
影响因子：
6.4
作者：
Behrens, Hannah M.;Lowe, Edward D.;Kleanthous, Colin
通讯作者：
Kleanthous, Colin
DOI：
10.1016/0048-4059(79)90082-1
发表时间：
1979-01-01
期刊：
PHYSIOLOGICAL PLANT PATHOLOGY
影响因子：
--
作者：
ELLIS, JG;KERR, A;SCHELL, J
通讯作者：
SCHELL, J