Intermolecular Amination of Allyl Alcohols with Sulfamates: Effective Utilization of Mercuric Catalyst
Intermolecular Amination of Allyl Alcohols with Sulfamates: Effective Utilization of Mercuric Catalyst
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烯丙醇与氨基磺酸盐的分子间胺化：汞催化剂的有效利用
DOI：
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
M. Nishizawa*
中科院分区：
文献类型：
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作者：
Hirofumi Yamamoto;Elisabeth Ho;Ikuo Sasaki;M. Mitsutake;Yuichi Takagi;H. Imagawa;M. Nishizawa*
在此，我们描述了烯丙醇与氨基磺酸酯的分子间胺化，氨基磺酸酯作为烯丙基胺化的氮亲核试剂尚未得到充分利用。氨基磺酸甲酯在三氟甲磺酸汞存在下是一种良好的亲核试剂，在室温下能高效地生成单烯丙基化产物。此外，固载汞催化剂硅苯基汞三氟甲磺酸酯对烯丙基胺化反应也表现出显著的催化活性。
Herein, we describe the intermolecular amination of allyl alcohols with sulfamates, which have been underutilized as nitrogen nucleophiles for allylic amination. Methyl sulfamate is a good nucleophile in the presence of mercuric triflate and efficiently generates monoallylation products in excellent yield at room temperature. Furthermore, the solid-supported mercuric catalyst silaphenyl mercuric triflate also showed remarkable catalytic activity for the allylic amination.
影响因子：
15
作者：
Trost BM;Malhotra S;Olson DE;Maruniak A;Du Bois J
通讯作者：
Du Bois J