Risperidone addition in serotonin reuptake inhibitor-resistant trichotillomania: three cases.

Risperidone addition in serotonin reuptake inhibitor-resistant trichotillomania: three cases.
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添加利培酮治疗耐血清素再摄取抑制剂的拔毛癖:三例。

DOI:
10.1089/cap.1999.9.43
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发表时间:
1999
影响因子:
1.9
通讯作者:
McDougle,CJ
McDougle,CJ
中科院分区:
医学3区
文献类型:
--
作者:
Epperson,CN;Fasula,D;Wasylink,S;Price,LH;McDougle,CJ

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开放标签添加低剂量典型(匹莫齐特)精神抑制剂被证明是有益的,在一些患者血清素再摄取抑制剂(SRI)难治性震颤躁狂症(TTM)。利培酮的潜在更良性的急性和长期副作用的概况,使其成为一个候选人的调查,在治疗TTM。我们报告了我们的经验,系统性增加了开放标签利培酮0.5至3毫克/天的3例SRI难治性TTM患者。所有三名患者都有一个强大的减少头发拉由临床医生评定的仪器测量。这些结果表明,利培酮加正在进行的治疗与SRI可能是一种有效的治疗策略,与SRI难治性TTM患者。
Open-label addition of a low-dose typical (pimozide) neuroleptic was shown to be beneficial in some patients with serotonin reuptake inhibitor (SRI)-refractory trichotillomania (TTM). Risperidone's potentially more benign acute and long-term side effect profile makes it a candidate for investigation in the treatment of TTM. We report our experience with the systematic addition of open-label risperidone 0.5 to 3 mg/day in three patients with SRI-refractory TTM. All three patients had a robust decrease in hair pulling as measured by clinician-rated instruments. These results suggest that risperidone addition to ongoing treatment with SRIs may be an effective treatment strategy for patients with SRI-refractory TTM.
拔毛癖:一种强迫症谱系障碍?
DOI: 10.1016/s0193-953x(18)30208-9
发表时间: 1992
影响因子: 1.7
作者:
S. Swedo;H. Leonard
通讯作者: H. Leonard
DOI: 10.1001/archpsyc.1989.01810110054008
发表时间: 1989-11
影响因子: --
作者:
W. Goodman;L. Price;S. Rasmussen;C. Mazure;P. Delgado;G. Heninger;D. Charney
通讯作者: W. Goodman;L. Price;S. Rasmussen;C. Mazure;P. Delgado;G. Heninger;D. Charney