SitesBase: a database for structure-based protein-ligand binding site comparisons.

SitesBase: a database for structure-based protein-ligand binding site comparisons.
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站点基础:用于基于结构的蛋白质 - 配体结合位点比较的数据库。

DOI:
10.1093/nar/gkj062
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发表时间:
2006-01-01
影响因子:
14.9
通讯作者:
Jackson RM
Jackson RM
中科院分区:
生物学2区
文献类型:
--
作者:
Gold ND;Jackson RM

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在细胞内,有许多成分支配着蛋白质的功能。在这里,我们主要关注小分子的分子识别和通过蛋白质-配体结合位点之间的相似性预测共同识别。SitesBase是一个易于访问的数据库,它使用简单,并保存了在蛋白质数据库中发现的已知配体结合位点之间结构相似性的信息。这些相似性呈现给更广泛的社区,使分子识别和潜在的蛋白质结构-功能关系的全面分析。SitesBase可在。
There are many components which govern the function of a protein within a cell. Here, we focus on the molecular recognition of small molecules and the prediction of common recognition by similarity between protein–ligand binding sites. SitesBase is an easily accessible database which is simple to use and holds information about structural similarities between known ligand binding sites found in the Protein Data Bank. These similarities are presented to the wider community enabling full analysis of molecular recognition and potentially protein structure–function relationships. SitesBase is accessible at .
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