Enhanced excitability of the corticospinal pathway of the ankle extensor and flexor muscles during standing in humans
Enhanced excitability of the corticospinal pathway of the ankle extensor and flexor muscles during standing in humans
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人体站立时踝伸肌和屈肌皮质脊髓通路的兴奋性增强
DOI：
10.1007/s00221-009-1874-6
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发表时间：
2009
影响因子：
2
通讯作者：
T.
中科院分区：
文献类型：
--
作者：
Obata;H.;Sekiguchi;H.;Nakazawa;K.;& Ohtsuki;T.
本研究的目的是探讨如何招募性质的皮质脊髓通路调制比目鱼肌（SOL）和胫骨前肌（TA）肌肉取决于姿势。在站立（STD）和坐姿（SIT）期间，通过经颅磁刺激在初级运动皮层上施加广泛的刺激强度，每块肌肉的背景活动水平相当。刺激强度和运动诱发电位的大小之间的关系通过Boltzmann S形函数进行评估，该函数的特征在于平台值、最大斜率和阈值。SOL肌肉STD期间的平台值和最大斜率显著高于SIT期间（STD与SIT，平台值：50.0 ± 21.8与33.9 ± 12.3 mV ms，最大斜率：1.6 ± 0.7与1.2 ± 0.5 mV ms/%最大刺激器输出）。在TA肌肉中也观察到类似的参数变化（STD与SIT，平台值：71.0 ± 22.9与41.4 ± 16.1 mV ms，最大斜率：5.0 ± 2.0与2.5 ± 0.7 mV ms/%最大刺激器输出）。阈值在两种条件和两种肌肉之间没有显着差异。这些结果表明，中枢神经系统需要一个不同的控制每一个姿势条件，即皮质脊髓通路的兴奋性和抑制性输入的相对平衡，以及在皮质脊髓通路的阈下边缘的神经元的数量增加，在STD期间相比，在SIT。
The purpose of this study was to investigate how the recruitment properties of the corticospinal pathway are modulated in the soleus (SOL) and tibialis anterior (TA) muscles depending on postures. A wide range of stimulus intensities were applied via transcranial magnetic stimulation over the primary motor cortex during standing (STD) and sitting (SIT) with a comparable background activity level in each muscle. The relationship between the stimulation intensities and the size of motor-evoked potentials was assessed by the Boltzmann sigmoid function, which is characterized by a plateau value, maximum slope, and threshold. The plateau value and maximum slope were significantly higher during STD than during SIT in the SOL muscle (STD vs. SIT, plateau value: 50.0 ± 21.8 vs. 33.9 ± 12.3 mV ms, maximal slope: 1.6 ± 0.7 vs. 1.2 ± 0.5 mV ms/% maximal stimulator output). Similar changes of the parameters were also observed in the TA muscle (STD vs. SIT, plateau value: 71.0 ± 22.9 vs. 41.4 ± 16.1 mV ms, maximal slope: 5.0 ± 2.0 vs. 2.5 ± 0.7 mV ms/% maximal stimulator output). The threshold did not differ significantly between the two conditions and both muscles. These results indicate that the central nervous system requires a different control for each postural condition; that is, the relative balance of the excitatory and inhibitory inputs to the corticospinal pathways as well as the number of neurons of subliminal fringe in the corticospinal pathway was increased during STD compared with those during SIT.
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人类第一背侧骨间肌对磁脑刺激反应的任务依赖性。
DOI：
--
发表时间：
1993
期刊：
Journal of Physiology
影响因子：
--
作者：
D. Flament;P. Goldsmith;C. J. Buckley;R. Lemon
通讯作者：
R. Lemon
影响因子：
5.5
作者：
Loram, ID;Maganaris, CN;Lakie, M
通讯作者：
Lakie, M
影响因子：
3.3
作者：
Pitcher, JB;Miles, TS
通讯作者：
Miles, TS
使用聚焦磁刺激研究意志和姿势活动期间人类比目鱼肌的皮质控制
影响因子：
2
作者：
B. Lavoie;Frederick W.J. Cody;C. Capaday
通讯作者：
C. Capaday
股四头肌调节对年轻人和老年人比目鱼肌运动神经元兴奋性的影响。
影响因子：
4.1
作者：
D. Koceja
通讯作者：
D. Koceja