Bacterial toxins: Offensive, defensive, or something else altogether?
Bacterial toxins: Offensive, defensive, or something else altogether?
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DOI:
10.1371/journal.ppat.1006452
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发表时间:
2017-09
期刊:
影响因子:
6.7
通讯作者:
Massey RC
中科院分区:
文献类型:
--
作者:
Rudkin JK;McLoughlin RM;Preston A;Massey RC
The secretion of proteins that damage host tissue is well established as integral to the infectious processes of many bacterial pathogens. However, recent advances in our understanding of the activity of toxins suggest that the attributes we have assigned to them from early in vitro experimentation have misled us into thinking of them as merely destructive tools. Here, we will discuss the multifarious ways in which toxins contribute to the lifestyle of bacteria and, by considering their activity from an evolutionary perspective, demonstrate how this extends far beyond their ability to destroy host tissue.
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