Laplacian manifold regularization method for fluorescence molecular tomography
Laplacian manifold regularization method for fluorescence molecular tomography
复制标题
荧光分子断层扫描的拉普拉斯流形正则化方法
DOI:
10.1117/1.jbo.22.4.045009
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发表时间:
2017-04
影响因子:
3.5
通讯作者:
贺小伟
中科院分区:
文献类型:
--
作者:
何雪磊;王晓东;易黄建;陈雁蓉;张旭;余景景;贺小伟
Sparse regularization methods have been widely used in fluorescence molecular tomography (FMT) for stable three-dimensional reconstruction. Generally, l1-regularization-based methods allow for utilizing the sparsity nature of the target distribution. However, in addition to sparsity, the spatial structure information should be exploited as well. A joint l1 and Laplacian manifold regularization model is proposed to improve the reconstruction performance, and two algorithms (with and without Barzilai–Borwein strategy) are presented to solve the regularization model. Numerical studies and in vivo experiment demonstrate that the proposed Gradient projection-resolved Laplacian manifold regularization method for the joint model performed better.than the comparative algorithm for l1 minimization method in both spatial aggregation and location accuracy.
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