Timed up and go test predicts mortality in older adults in Peru: a population-based cohort study.

Timed up and go test predicts mortality in older adults in Peru: a population-based cohort study.
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DOI:
10.1186/s12877-022-02749-6
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发表时间:
2022-01-18
期刊:
影响因子:
4.1
通讯作者:
Ortiz PJ
Ortiz PJ
中科院分区:
医学2区
文献类型:
--
作者:
Ascencio EJ;Cieza-Gómez GD;Carrillo-Larco RM;Ortiz PJ

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虽然有证据表明存在既定的风险因素(例如,由于高血压和高死亡率风险的存在,在低收入和中等收入国家,对老年人的其他功能参数(如计时起身和行走测试和步态速度)的研究较少。我们的目的是研究这些流动性测试的预测死亡率在人口的老年人在秘鲁。基于人群的前瞻性队列研究(2013-2020年)。秘鲁利马社区60岁以上人群的随机抽样。所有临床评价均由老年病学家进行,实验室检查在当地医院进行。在国家生命登记系统中寻找参与者,我们整理了死亡原因(ICD-10)和死亡日期。我们进行了一个嵌套的前向多变量考克斯比例风险模型,以确定所有潜在的预测因素的全因,传染性和非传染性疾病的死亡率。基线时,有501名老年人(平均年龄70.6岁,62.8%为女性),427人提供了完整的随访信息。平均随访时间为46.5个月(SD = 25.3)。在多变量模型中,定时启动和启动测试与全因死亡率的较高风险相关(HR = 1.05; 95% CI:1.02-1.09)。对于病因特异性死亡率,心脏病史(HR = 2.25; 95%CI:1.07-4.76)和年龄(HR = 1.05; 95%CI:1.01-1.09)是非传染性疾病死亡率的预测因素。除了老年人群死亡率的既定风险因素外,功能参数Timed Up and Go测试作为全因死亡率的相关预测因子。在线版本包含补充材料,可通过10.1186/s12877-022-02749-6获得。
While there is evidence about stablished risk factors (e.g., raised blood pressure) and higher mortality risk in older population, less has been explored about other functional parameters like the Timed Up and Go test and the Gait Speed in older people at low- and middle-income countries. We aimed to study these mobility tests as predictors of mortality in a population of older people in Peru. Population-based prospective cohort study (2013–2020). Random sampling of people aged 60+ years in a community of Lima, Peru. Geriatricians conducted all clinical evaluations and laboratory tests were conducted in the local hospital. Participants were sought in the national vital registration system, and we collated cause (ICD-10) and date of death. We conducted a nested forward multivariate Cox proportional hazard model to identify all potential predictors of all-cause, communicable and non-communicable diseases mortality. At baseline, there were 501 older people (mean age 70.6 and 62.8% were women), complete follow-up information was available from 427 people. Mean follow-up time was 46.5 months (SD = 25.3). In multivariate models, the Timed Up and Go test was associated with higher risk of all-cause mortality (HR = 1.05; 95% CI: 1.02–1.09). For cause-specific mortality, history of heart disease (HR = 2.25; 95% CI: 1.07–4.76) and age in years (HR = 1.05; 95% CI: 1.01–1.09) were predictors of non-communicable diseases mortality. In addition to established risk factors for mortality in older population, the Timed Up and Go test, a functional parameter, raised as a relevant predictor of all-cause mortality. The online version contains supplementary material available at 10.1186/s12877-022-02749-6.
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