Chemical Composition, Antibacterial and Phytotoxic Activities of Peganum harmala Seed Essential Oils from Five Different Localities in Northern Africa.

Chemical Composition, Antibacterial and Phytotoxic Activities of Peganum harmala Seed Essential Oils from Five Different Localities in Northern Africa.
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来自北非五个不同地区的Peganum Harmala种子精油的化学成分,抗菌和植物毒性活性。

DOI:
10.3390/molecules21091235
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发表时间:
2016-09-15
期刊:
Molecules (Basel, Switzerland)
影响因子:
--
通讯作者:
Khadhr M
Khadhr M
中科院分区:
其他
文献类型:
--
作者:
Apostolico I;Aliberti L;Caputo L;De Feo V;Fratianni F;Nazzaro F;Souza LF;Khadhr M

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骆驼蓬,也被称为叙利亚芸香或Pègano,是属于蒺藜科的草本植物,广泛用于传统医学。采用GC和GC-MS分析方法对来自北方5个不同地区(阿尔及利亚、埃及、利比亚、摩洛哥和突尼斯)的骆驼蓬种子挥发油的化学成分进行了研究。共鉴定出105种化合物,主要成分为含氧单萜和含氧倍半萜。丁香酚是所有油中的主要成分。精油的抗微生物活性针对一些细菌菌株进行测定:金黄色葡萄球菌(DSM 25693)、蜡样芽孢杆菌(DSM 4313)、蜡样芽孢杆菌(DSM 4384)、大肠杆菌(DMS 857)和铜绿假单胞菌(ATCC 50071)。所有的油表现出不同的抑制活性。在二十世纪,这是一个重要的结果;我们需要可能的新植物药,因为抗微生物药物的耐药性问题已经变得明显。此外,评价精油对萝卜的萌发和初始胚根生长的可能的体外植物毒性活性,独行菜,和芸香(Ruta graveolens L.)结果表明,种子萌发和胚根伸长对油脂敏感。
Peganum harmala L., also known as Syrian rue or Pègano, is a herbaceous plant belonging to the Zygohpyllaceae family, and is widely used in traditional medicine. The chemical composition of essential oils of P. harmala seeds from five different regions of Northern Africa (Algeria, Egypt, Libya, Morocco and Tunisia) was studied by GC and GC-MS analyses. A total of 105 compounds were identified, the main components being oxygenated monoterpenes and oxygenated sesquiterpenes. Eugenol is the main component in all oils. The antimicrobial activity of the essential oils was assayed against some bacterial strains: Staphylococcus aureus (DSM 25693), Bacillus cereus (DSM 4313), Bacillus cereus (DSM4384), Escherichia coli (DMS 857) and Pseudomonas aeruginosa (ATCC 50071). All the oils showed different inhibitory activity. In the twentieth century this is an important result; we need possible new botanical drugs because the problem of resistance to antimicrobial drugs has become apparent. Moreover, the essential oils were evaluated for their possible in vitro phytotoxic activity against germination and initial radicle growth of Raphanus sativus L., Lepidium sativum L., and Ruta graveolens L. The results showed that both germination and radical elongation were sensitive to the oils.
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