Attention-deficit hyperactivity disorder diagnoses and prescriptions in UK primary care, 2000-2018: population-based cohort study.
Attention-deficit hyperactivity disorder diagnoses and prescriptions in UK primary care, 2000-2018: population-based cohort study.
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DOI：
10.1192/bjo.2023.512
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发表时间：
2023-07-17
期刊：
影响因子：
5.4
通讯作者：
Petersen, Irene
中科院分区：
文献类型：
--
作者：
McKechnie, Douglas G. J.;O'Nions, Elizabeth;Dunsmuir, Sandra;Petersen, Irene
关键词：
在英国，被诊断为注意力缺陷多动障碍（ADHD）的比率可能正在上升。估计英国成人和儿童初级保健中ADHD诊断和ADHD处方的发病率和患病率。我们使用IQVIA医学研究数据（英国初级保健数据库）进行了一项队列研究。计算了2000年至2018年间3-99岁人群的ADHD诊断率和ADHD处方率，并按年龄、性别、社会剥夺状况和日历年进行了分析。在7 655 931人中，35 877人（0.5%）被诊断为ADHD；18 518人（0.2%）接受了ADHD药物处方。男性的诊断率和处方率高于女性，儿童高于成人，以及贫困状况（最贫困的五分之一比最贫困的五分之一几乎翻了一番）。到2018年，男孩的ADHD诊断比例为255 / 10000 (95% CI 247-263)，女孩为67.7 / 10000 (95% CI 63.5-71.9)；成人中，男性为74.3 / 10000 (95%CI 72.3-76.2)，女性为20 / 10000 （95%CI 19.0-21.0）。相应的处方数据为：男孩156 / 10000 (95% CI 150-163)，女孩36.8 / 10000 (95% CI 33.8-40.0)，男性13.3 / 10000 (95% CI 12.5-14.1)，女性4.5 / 10000 （95% CI 4.1-5.0）。从2000年到2018年，除3至5岁儿童外，所有年龄组ADHD诊断和处方的发病率和流行率都有所增加。儿童的绝对增幅最高，但成年人的相对增幅最大（例如，在18-29岁的男性中，诊断和处方分别增加了约20倍和近50倍）。ADHD诊断和药物治疗的发病率和流行率在儿童中最高。从比例上看，2000年至2018年期间，成年人的发病率增幅最大。ADHD的诊断和处方与社会经济剥夺有关。
Rates of diagnosed attention-deficit hyperactivity disorder (ADHD) may be increasing in the UK. Estimate incidence and prevalence of ADHD diagnoses and ADHD prescriptions in UK adults and children in primary care. We conducted a cohort study using IQVIA Medical Research Data, a UK primary care database. Rates of ADHD diagnoses and ADHD prescriptions were calculated between 2000 and 2018 for individuals aged 3–99 years, analysed by age, gender, social deprivation status and calendar year. Of 7 655 931 individuals, 35 877 (0.5%) had ADHD diagnoses; 18 518 (0.2%) received ADHD medication prescriptions. Diagnoses and prescription rates were greater in men versus women, children versus adults, and deprivation status (nearly double in most deprived versus least deprived quintile). By 2018, the proportion of ADHD diagnoses was 255 per 10 000 (95% CI 247–263) in boys and 67.7 per 10 000 (95% CI 63.5–71.9) in girls; for adults, it was 74.3 per 10 000 (95% CI 72.3–76.2) in men and 20 per 10 000 (95%CI 19.0–21.0) in women. Corresponding figures for prescriptions were 156 per 10 000 (95% CI 150–163) in boys, 36.8 per 10 000 (95% CI 33.8–40.0) in girls, 13.3 per 10 000 (95% CI 12.5–14.1) in men and 4.5 per 10 000 (95% CI 4.1–5.0) in women. Except among 3- to 5-year-olds, the incidence and prevalence of ADHD diagnoses and prescriptions have increased from 2000 to 2018 in all age groups. The absolute increase was highest in children, but the relative increase was largest among adults (e.g. among men aged 18–29 years, approximately 20-fold and nearly 50-fold increases in diagnoses and prescriptions, respectively). The incidence and prevalence of both ADHD diagnoses and medication are highest among children. Proportionally, rates increased most among adults during 2000–2018. ADHD diagnoses and prescriptions are associated with socioeconomic deprivation.
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患有注意力缺陷多动症障碍（ADHD）的儿童和成人服务之间的过渡：来自英国国家监视研究的发现。
DOI：
10.1192/bjp.2019.131
发表时间：
2020-11
期刊：
The British journal of psychiatry : the journal of mental science
影响因子：
--
作者：
Eke H;Ford T;Newlove-Delgado T;Price A;Young S;Ani C;Sayal K;Lynn RM;Paul M;Janssens A
通讯作者：
Janssens A
影响因子：
5.2
作者：
Melhuish, E.;Belsky, J.;Barnes, J.
通讯作者：
Barnes, J.
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影响因子：
2.9
作者：
Beau-Lejdstrom R;Douglas I;Evans SJ;Smeeth L
通讯作者：
Smeeth L
影响因子：
4.4
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通讯作者：
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影响因子：
2.6
作者：
Horsfall, Laura;Walters, Kate;Petersen, Irene
通讯作者：
Petersen, Irene