Quantification of condylar resorption in temporomandibular joint osteoarthritis.

Quantification of condylar resorption in temporomandibular joint osteoarthritis.
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DOI:
10.1016/j.tripleo.2010.01.008
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发表时间:
2010-07
期刊:
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
影响因子:
--
通讯作者:
Phillips C
Phillips C
中科院分区:
其他
文献类型:
--
作者:
Cevidanes LH;Hajati AK;Paniagua B;Lim PF;Walker DG;Palconet G;Nackley AG;Styner M;Ludlow JB;Zhu H;Phillips C

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本研究旨在探讨骨关节炎(OA)患者和无症状颞下颌关节(TMJ)患者髁突形态的变化及其与疼痛强度和持续时间的相关性。根据29例女性颞下颌关节骨性关节炎患者(颞下颌关节紊乱病研究诊断标准III组)和36例女性无症状受试者的锥形束CT图像构建下颌髁状突的三维表面模型。形状对应用于定位和量化髁突形态。使用基于协方差矩阵的Hotelling T2度量和Pearson相关性,采用MANCOVA分析进行统计分析。骨性关节炎髁突形态与无症状髁突相比差异有统计学意义(p<0.05)。OA髁突的三维形态变化与疼痛强度和持续时间显著相关。髁突形态的3D定量显示OA和无症状髁突之间存在显著差异,骨吸收变化的程度与疼痛的严重程度和持续时间有关。
This study was performed to determine the condylar morphological variation of osteoarthritic (OA) and asymptomatic temporomandibular joints (TMJ) and to determine its correlation with pain intensity and duration. Three dimensional surface models of mandibular condyles were constructed from Cone-Beam CT images of 29 female patients with TMJ OA (Research Diagnostic Criteria for Temporomandibular Disorders Group III) and 36 female asymptomatic subjects. Shape Correspondence was used to localize and quantify the condylar morphology. Statistical analysis was performed with MANCOVA analysis using Hotelling T2 metric based on covariance matrices, and Pearson correlation. OA condylar morphology was statistically significantly different from the asymptomatic condyles (p<0.05). 3D morphological variation of the OA condyles was significantly correlated with pain intensity and duration. 3D quantification of condylar morphology revealed profound differences between OA and asymptomatic condyles and the extent of the resorptive changes paralleled pain severity and duration.
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