Comment on "Systematic Review and Meta-Analysis of Diagnostic Accuracy of miRNAs in Patients with Pancreatic Cancer".
Comment on "Systematic Review and Meta-Analysis of Diagnostic Accuracy of miRNAs in Patients with Pancreatic Cancer".
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DOI：
10.1155/2018/6904569
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Baxi S
中科院分区：
文献类型：
--
作者：
Jayaraj R;Kumarasamy C;Madhav MR;Pandey V;Sabarimurugan S;Ramesh N;Gothandam KM;Baxi S
胰腺癌是最恶性和侵袭性的癌症之一，生存率低，诊断基于非特异性肿瘤生物标志物。因此，Sun等人的出版物“Systematic Review and Meta-Analysis of Diagnostic Accuracy of miRNAs in Patients with Pancreatic Cancer”具有突出潜在miRNAs作为胰腺癌高准确度诊断标志物的极好潜力[1]。然而，我们认为，尽管Sun等人进行了全面的研究，有一些改进可以进一步提高该论文的临床应用。就目前而言，我们认为这项研究存在一些问题，阻止了Sun等人的此类应用。作者指出，有必要测量miRNA在胰腺癌中的诊断价值。然而，该领域的研究已经存在[2-4]。尽管以前的研究报告了不确定的结果，但作者仍然需要强调这项研究与以前的出版物之间的差异，并详细说明其相对于以前此类研究的益处，而不仅仅是说明不一致的结果。
Pancreatic cancer is one of the most malignant and aggressive cancers, with poor survival rates and diagnosis being based on nonspecific tumour biomarkers. Due to this, the publication,“Systematic Review and Meta-Analysis of Diagnostic Accuracy of miRNAs in Patients with Pancreatic Cancer”, by Sun et al. has excellent potential for highlighting potential miRNAs as high-accuracy diagnostic markers in pancreatic cancer [1]. However, we believe that despite the comprehensive study conducted by Sun et al., there are a few improvements that could be made to heighten the clinical utility of the paper further. As it stands, we believe that the study has some issues that prevent such applications of Sun et al.’s study.The authors have stated that there is a need to measure the diagnostic value of miRNA in pancreatic cancer. However, previous studies in the field already exist [2–4]. Despite the previous studies reporting inconclusive results, the authors still need to highlight the differences between this study and previous publications, as well as elaborate more on its benefits over previous such studies, other than merely stating discordant results.
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DOI：
10.5114/aoms.2012.31609
发表时间：
2012-11-09
期刊：
Archives of medical science : AMS
影响因子：
--
作者：
Wan C;Shen Y;Yang T;Wang T;Chen L;Wen F
通讯作者：
Wen F
影响因子：
7.2
作者：
Deeks, JJ;Macaskill, P;Irwig, L
通讯作者：
Irwig, L
影响因子：
4.8
作者：
Lee J;Kim KW;Choi SH;Huh J;Park SH
通讯作者：
Park SH
影响因子：
--
作者：
Ding, Zhongyang;Wu, Haorong;Ji, Dongdong
通讯作者：
Ji, Dongdong
使用荟萃分析对胰腺癌进行临床相关的循环 microRNA 分析研究。
影响因子：
--
作者：
Pei Z;Liu SM;Huang JT;Zhang X;Yan D;Xia Q;Ji C;Chen W;Zhang X;Xu J;Wang J
通讯作者：
Wang J