CHROMIXS: automatic and interactive analysis of chromatography-coupled small-angle X-ray scattering data.
CHROMIXS: automatic and interactive analysis of chromatography-coupled small-angle X-ray scattering data.
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DOI:
10.1093/bioinformatics/btx846
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发表时间:
2018-06-01
期刊:
影响因子:
--
通讯作者:
Svergun DI
中科院分区:
文献类型:
--
作者:
Panjkovich A;Svergun DI
Size-exclusion chromatography (SEC) coupled to small-angle X-ray scattering (SAXS), also known as inline SEC-SAXS, is being increasingly used for the structural analysis of biological macromolecules, complexes and mixtures in solution. A single SEC-SAXS run generates thousands of individual SAXS profiles from the eluting solute and their analysis requires a correct identification of buffer and sample regions, a rather laborous task. We present CHROMIXS (as in CHROMatography Inline X-ray Scattering), a program for rapid reduction and analysis, both automatically and interactively, of SEC-SAXS data. CHROMIXS is freely available to academic users as part of the ATSAS software suite (www.embl-hamburg.de/biosaxs/download.html).
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