Normative visual acuity in Chinese preschoolers aged 36 to <48 months as measured with the linear HOTV chart: the Yuhuatai Pediatric Eye Disease Study.
Normative visual acuity in Chinese preschoolers aged 36 to <48 months as measured with the linear HOTV chart: the Yuhuatai Pediatric Eye Disease Study.
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DOI：
10.1136/bmjopen-2016-014866
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发表时间：
2017-07-09
期刊：
影响因子：
2.9
通讯作者：
Liu H
中科院分区：
文献类型：
--
作者：
Zhu H;Huang D;Sun Q;Ding H;Bai J;Chen J;Chen X;Wang Y;Zhang X;Wang J;Li X;Liu H
目的：研究中国36 ~<48个月学龄前儿童裸眼视力（UCVA）的正常值，并评价其在视力转诊中的有效性。在雨花台儿童眼病研究的一个基于人群的儿童队列中，使用线性HOTV图测量UCVA，然后进行其他眼科检查。参考人群定义为无眼科异常或屈光不正的儿童。从参考人群中获得标准UCVA。UCVA转诊临界值定义为UCVA标准分布的最低第五百分位数。分析队列由1606名年龄在36至<48个月的中国学龄前儿童组成。其中，共有791名儿童被纳入参考人群。参考人群UCVA分布的第5、50和95位数分别为20/40、20/32和20/25。UCVA随年龄增加而改善（p<0.0001），但如果出现早产则恶化（p=0.041）。使用第五百分位数，从参考人群中UCVA截止产生的转诊率为26.9%，在一般人群中，并检测到超过86%的弱视病例。我们建议以线性HOTV视力表测量的UCVA不超过20/40作为中国36 ~<48个月学龄前儿童的参考界值。大多数弱视病例都可以用这个年龄特异性和视力表特异性UCVA截止值来识别。
To document population-based normative data for uncorrected visual acuity (UCVA) in Chinese preschoolers aged 36 to <48 months without any sight-affecting abnormalities and to evaluate its effectiveness for vision referral. In a population-based cohort of children in the Yuhuatai Pediatric Eye Disease Study, UCVA was measured by using the linear HOTV chart, followed by other ocular examinations. Reference population was defined as children without ophthalmic abnormalities or refractive error. Normative UCVA was obtained from the reference population. The UCVA referral cut-off was defined as the lowest fifth percentile of the normative distribution of UCVA. The analysis cohort consisted of 1606 Chinese preschoolers aged 36 to <48 months. Among them, a total of 791 children were included in the reference population. The 5th, 50th and 95th percentiles of the UCVA distribution in the reference population were 20/40, 20/32 and 20/25, respectively. UCVA improved with increasing age (p<0.0001), but worsen if prematurity was presented (p=0.041). Using the fifth percentile, UCVA cut-off from the reference population generated referral rates of 26.9% in the general population, and detected more than 86% of amblyopia cases. We propose that UCVA no better than 20/40 measured by linear HOTV chart should be a referral cut-off for Chinese preschoolers aged 36 to <48 months. Most amblyopia cases can be identified with this age-specific and chart-specific UCVA cut-off.
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