Rethinking stress resilience.

Rethinking stress resilience.
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DOI:
10.1016/j.tins.2021.09.005
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发表时间:
2021-12
影响因子:
15.9
通讯作者:
Bhatnagar S
Bhatnagar S
中科院分区:
医学1区
文献类型:
--
作者:
Bhatnagar S

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在临床和临床前研究中,对压力性生活事件的恢复力受到了相当大的关注。许多神经基质已被确定为puronectin介导的压力恢复力。然而,在如何定义和研究复原力方面仍然存在相当大的差异。本文旨在探讨社会心理学,公共卫生和相关领域中如何定义和概念化弹性,以更好地了解神经生物学背景下的压力弹性,并将弹性与其他应对压力体验的模式区分开来。通过临床和应用科学的透镜理解弹性可能会导致识别更强大和可重复的神经基质,尽管仍然存在许多挑战。
Resilience to stressful life events has received considerable attention in both clinical and preclinical studies. A number of neural substrates have been identified as putatively mediating resilience to stress. However, there remains considerable diversity in how resilience is defined and studied. This article aims to examine how resilience is defined and conceptualized in social psychology, public health, and related fields, to better inform the understanding of stress resilience in the neurobiological context and to differentiate resilience from other patterns of response to stressful experiences. An understanding of resilience through the lens of clinical and applied sciences is likely to lead to the identification of more robust and reproducible neural substrates, though many challenges remain.
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