Discerning Functional Connections in the Pulsed Neural Networks with the Dynamic Bayesian Network Structure Search Method Based on a Genetic Algorithm

Discerning Functional Connections in the Pulsed Neural Networks with the Dynamic Bayesian Network Structure Search Method Based on a Genetic Algorithm
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基于遗传算法的动态贝叶斯网络结构搜索方法识别脉冲神经网络中的功能连接

DOI:
10.1089/cmb.2019.0147
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发表时间:
2019-11
影响因子:
1.7
通讯作者:
Dong Chao Yi
Dong Chao Yi
中科院分区:
生物学4区
文献类型:
--
作者:
Dong Chaoxuan;Chen Xiao Yan;Dong Chao Yi

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It is important to explore potential structural characteristics of biological networks and regulatory mechanisms of network behaviors at the system level. In this study, a dynamic Bayesian network structure search method (DBNSSM) based on a genetic algorithm is employed to infer and locate functional connections in pulsed neural networks (PNNs) as typical artificial neural networks. In the process of network structure searching, a minimum description length score is calculated for each candidate network structure. The score indicates two characteristics of the network structure: (1) the likelihood based on network dynamic response data and (2) the complexity. Both should be considered together on selecting network structures. The DBNSSM is applied to analyze time-series data from PNNs, thereby discerns functional connections showing network structures collectively. It is feasible to analyze multichannel electrophysiological data of biological neural networks using the DBNSSM.
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