Radiofrequency and microwave ablation in a porcine liver model: non-contrast CT and ultrasound radiologic-pathologic correlation.
Radiofrequency and microwave ablation in a porcine liver model: non-contrast CT and ultrasound radiologic-pathologic correlation.
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DOI：
10.1080/02656736.2020.1784471
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Brace CL
中科院分区：
文献类型：
--
作者：
Ziemlewicz TJ;Hinshaw JL;Lubner MG;Knott EA;Willey BJ;Lee FT Jr;Brace CL
本研究的目的是比较术中射频（RF）和微波消融在非造影CT（NCCT）和超声上的表现与病理性坏死区。使用1）140 W微波、2）70 W微波或3）200 W射频（各n=7）在猪肝中进行了21次5 min体内消融。在消融期间1、3和5分钟以及消融后2、5和10分钟同时获得CT和US图像。在超声图像平面上对每个消融进行切片，并进行活体染色以描绘细胞坏死。将CT重新格式化为与超声换能器相同的平面，并测量每个时间点的气体和低回声/低衰减区的横向直径。使用Student t检验和线性回归比较CT、超声和大体病理直径测量值。超声图像上可见气体和低回声区对病理消融区的预测能力高于NCCT图像（P<0.05）。在超声（微波平均3.2mm，射频平均6.4mm）和NCCT（微波7.6mm，射频13.9mm）图像上，坏死区大于可见气体区（p < 0.05）。与射频消融相比，超声可见气体区和低回声区更能预测微波消融的病理（p < 0.05）。在能量输送过程中评价图像时，US比CT和微波更准确-根据与平面内病理的相关性，比RF消融更可预测。
The goal of this study was to compare intra-procedural radiofrequency (RF) and microwave ablation appearance on non-contrast CT (NCCT) and ultrasound to the zone of pathologic necrosis. Twenty-one 5-minute ablations were performed in vivo in swine liver with 1) microwave at 140 W, 2) microwave at 70 W, or 3) RF at 200 W (n=7 each). CT and US images were obtained simultaneously at 1, 3, and 5 minutes during ablation and 2, 5, and 10 minutes post-ablation. Each ablation was sectioned in the plane of the ultrasound image and underwent vital staining to delineate cellular necrosis. CT was reformatted to the same plane as the ultrasound transducer and transverse diameters of gas and hypoechoic/hypoattenuating zones at each time point were measured. CT, ultrasound and gross pathologic diameter measurements were compared using Student’s t-tests and linear regression. Visible gas and the hypoechoic zone on US images were more predictive of the pathologic ablation zone than on NCCT images (P<0.05). The zone of necrosis was larger than the zone of visible gas on US (mean 3.2 mm for microwave, 6.4 mm for RF) and NCCT (7.6 mm microwave, 13.9 mm RF) images (p < 0.05). The zone of visible gas and hypoechoic zone on US are more predictive of pathology with microwave ablations when compared with RF ablations (p < 0.05). When evaluating images during energy delivery, US is more accurate than CT and microwave- more predictable than RF-ablation based on correlation with in-plane pathology.
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DOI：
10.1016/j.jvir.2016.01.136
发表时间：
2016-05
期刊：
Journal of vascular and interventional radiology : JVIR
影响因子：
--
作者：
Potretzke TA;Ziemlewicz TJ;Hinshaw JL;Lubner MG;Wells SA;Brace CL;Agarwal P;Lee FT Jr
通讯作者：
Lee FT Jr
影响因子：
3.1
作者：
Amabile, Claudio;Ahmed, Muneeb;Goldberg, S. Nahum
通讯作者：
Goldberg, S. Nahum
影响因子：
6.6
作者：
Campbell, Steven;Uzzo, Robert G.;Pierorazio, Philip M.
通讯作者：
Pierorazio, Philip M.
影响因子：
1.9
作者：
Wells SA;Hinshaw JL;Lubner MG;Ziemlewicz TJ;Brace CL;Lee FT Jr
通讯作者：
Lee FT Jr
影响因子：
3.7
作者：
Sotirchos, Vlasios S.;Fujisawa, Sho;Sofocleous, Constantinos T.
通讯作者：
Sofocleous, Constantinos T.