Proper cold stimulation starting at an earlier age can enhance immunity and improve adaptability to cold stress in broilers.
Proper cold stimulation starting at an earlier age can enhance immunity and improve adaptability to cold stress in broilers.
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从小年龄开始适当的冷刺激可以增强肉鸡的免疫力，提高对冷应激的适应能力
DOI：
10.3382/ps/pez570
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发表时间：
2020-01
期刊：
影响因子：
4.4
通讯作者：
Bao J
中科院分区：
文献类型：
--
作者：
Su Y;Li S;Xin H;Li J;Li X;Zhang R;Li J;Bao J
The effects of long-term cold stimulation on the immune function of ileum and adaptability to cold stress in broilers were examined. A total of 360 Arbor Acres broilers was divided into 3 groups and four replicates per group. C (control) was reared in normal thermal environment. C-3 and C-12 (treatments) were kept in cold condition of 3 or 12°C lower than the temperature of C from days 8 to 42. At day 42, all the groups were exposed to an acute cold stress challenge, designated as S, S-3, and S-12. The mRNA levels of immune molecules and heat shock proteins as well as oxidative stress-related indicators in ileum tissues, and immunoglobulins contents in serum were examined at 14, 42, and 43 d of age. The C-3 regimen had no adverse effect on production performance, whereas the C-12 regimen reduced the production performance relative to C (P < 0.05). At day 42, C-3 had higher levels of immune indexes (P < 0.05), whereas C-12 had lower levels than C (P < 0.05). No differences in levels of oxidative stress-related indicators were found between C and C-3 at day 42 (P > 0.05). S-3 had higher levels of immune indexes and lower levels of oxidative stress-related indicators (P < 0.05), as compared to S and S-12. The results suggest that 34 d of cold stimulation at 3°C lower than the normal temperature had no adverse impacts on production performance but enhanced the immunity of ileum and adaptability to acute cold challenge in broilers.
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影响因子：
--
作者：
Gao M;Li Y;Zheng A;Xue X;Chen L;Kong Y
通讯作者：
Kong Y
影响因子：
5.8
作者：
Chi, Qianru;Liu, Tianqi;Li, Shu
通讯作者：
Li, Shu
影响因子：
4.4
作者：
Lee, Mi Ok;Jang, Hyun-Jun;Womack, James E.
通讯作者：
Womack, James E.
影响因子：
2.1
作者：
Malan, Melissa;Serem, June C.;Gaspar, Anabella R. M.
通讯作者：
Gaspar, Anabella R. M.
影响因子：
15.1
作者：
CARR, DJJ;WOOLLEY, TW;BLALOCK, JE
通讯作者：
BLALOCK, JE