Role of Nod2 in the development of Crohn's disease.
Role of Nod2 in the development of Crohn's disease.
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DOI:
10.1016/j.micinf.2009.06.005
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发表时间:
2009-10
影响因子:
5.8
通讯作者:
Ma X
中科院分区:
文献类型:
--
作者:
Yamamoto S;Ma X
Crohn’s Disease (CD) is caused by a loss of the regulatory capacity of the immune apparatus. Nod2 is an intracellular bacterial sensor and its mutations are associated with the development of CD. Here we summarize recent and controversial findings about the role of the Nod2 mutants in the disease process.
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