Prenatal methamphetamine exposure and short-term maternal and infant medical outcomes.
Prenatal methamphetamine exposure and short-term maternal and infant medical outcomes.
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DOI：
10.1055/s-0032-1304818
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发表时间：
2012-05
影响因子：
2
通讯作者：
Lester BM
中科院分区：
文献类型：
--
作者：
Shah R;Diaz SD;Arria A;LaGasse LL;Derauf C;Newman E;Smith LM;Huestis MA;Haning W;Strauss A;Della Grotta S;Dansereau LM;Roberts MB;Neal C;Lester BM
检查产前暴露于甲基苯丙胺（MA）的母婴医疗结果。在婴儿发育、环境和生活方式（IDEAL）研究中纳入了112对母婴（204对暴露于ma的母婴和208对未暴露于ma的母婴）。暴露是由孕妇在怀孕期间的自我报告和/或胎粪毒理学阳性来确定的。产妇访谈评估了产前药物使用、妊娠过程和社会人口信息。病历回顾提供了病史、产科并发症、婴儿结局和出院安排。与对照组母亲相比，使用ma的母亲更有可能贫穷，有精神障碍/情绪疾病，产前护理较少，并且更不可能母乳喂养婴儿。在调整协变量后，暴露于ma的婴儿更有可能表现出吮吸不良，头围和长度更小，需要新生儿重症监护病房（NICU）入院，并转介到儿童保护服务（CPS）。先前缺乏足够对照组或协变量调整的研究报告的几个结果在本研究中没有显着差异。产前MA暴露与母亲精神障碍/情绪疾病、吸吮不良、NICU入院和CPS参与有关，MA暴露的婴儿更不可能母乳喂养；然而，没有许多严重的并发症，如胎儿窘迫、慢性高血压、先兆子痫、前置胎盘、胎盘早剥和心脏缺陷，表明混杂变量影响了先前的研究。
Examine maternal and infant medical outcomes of prenatal exposure to methamphetamine (MA). Four hundred and twelve mother-infant pairs (204 MA-exposed and 208 unexposed matched comparisons) were enrolled in the Infant Development, Environment and Lifestyle (IDEAL) study. Exposure was determined by maternal self-report during this pregnancy and/or positive meconium toxicology. Maternal interviews assessed prenatal drug use, pregnancy course, and sociodemographic information. Medical chart reviews provided medical history, obstetric complications, infant outcomes, and discharge placement. MA-using mothers were more likely to be poor, to have a psychiatric disorder/emotional illness and less prenatal care, and to be less likely to breast-feed their infant than comparison mothers. After adjusting for covariates, MA-exposed infants were more likely to exhibit poor suck, to have smaller head circumferences and length, to require neonatal intensive care unit (NICU) admission, and to be referred to child protective services (CPS). Several outcomes previously reported from studies that lacked adequate control groups or adjustment for covariates were not significantly different in this study. Prenatal MA exposure is associated with maternal psychiatric disorder/emotional illness, poor suck, NICU admission, and CPS involvement, and MA-exposed infants were less likely to be breast-fed; however, the absence of many serious complications, such as fetal distress, chronic hypertension, preeclampsia, placenta previa, abruptio placentae, and cardiac defects, suggests confounding variables influenced prior studies.
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影响因子：
7.2
作者：
Good, Meadow M.;Solt, Ido;Kim, Matthew J.
通讯作者：
Kim, Matthew J.
影响因子：
9.8
作者：
Bauer, CR;Shankaran, S;Verter, J
通讯作者：
Verter, J
DOI：
10.1111/j.1651-2227.1978.tb16283.x
发表时间：
1978-01-01
期刊：
ACTA PAEDIATRICA SCANDINAVICA
影响因子：
--
作者：
ERIKSSON, M;LARSSON, G;ZETTERSTROM, R
通讯作者：
ZETTERSTROM, R
影响因子：
8
作者：
Shankaran, S;Das, A;Smeriglio, V
通讯作者：
Smeriglio, V
影响因子：
8
作者：
Richardson, GA;Hamel, SC;Day, NL
通讯作者：
Day, NL