DOT Diary: Developing a Novel Mobile App Using Artificial Intelligence and an Electronic Sexual Diary to Measure and Support PrEP Adherence Among Young Men Who Have Sex with Men.
DOT Diary: Developing a Novel Mobile App Using Artificial Intelligence and an Electronic Sexual Diary to Measure and Support PrEP Adherence Among Young Men Who Have Sex with Men.
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DOI：
10.1007/s10461-020-03054-2
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发表时间：
2021-04
影响因子：
4.4
通讯作者：
Buchbinder S
中科院分区：
文献类型：
--
作者：
Liu AY;Laborde ND;Coleman K;Vittinghoff E;Gonzalez R;Wilde G;Thorne AL;Ikeguchi E;Shafner L;Sunshine L;van der Straten A;Siegler AJ;Buchbinder S
男男性行为青年（YMSM）极易感染艾滋病毒。虽然暴露前预防（PrEP）已被证明是有效的，但YMSM的依从性很低，难以准确衡量。我们与一家医疗保健公司合作，配置了一个自动化直接观察治疗（aDOT）平台，用于监测和支持PrEP的使用。基于54名YMSM在焦点小组中表达的兴趣，我们将aDOT与电子性日记相结合，以提供有关性行为期间保护水平的反馈，并激励应用程序的使用。在旧金山弗朗西斯科和亚特兰大对20名YMSM进行的为期8周的优化试点中，发现该应用程序的可接受性很高，系统可用性量表评分中位数在“优秀”范围内（80/100）。应用程序的使用率很高，基于aDOT确认的剂量，PrEP依从性的中位数为91%。大多数（84%）参与者报告该应用程序有助于采取PrEP。这些有希望的发现支持在未来的有效性研究中进一步评估DOT日记。
Young men who have sex with men (YMSM) are highly vulnerable to HIV. While pre-exposure prophylaxis (PrEP) has demonstrated effectiveness, adherence has been low among YMSM and difficult to measure accurately. In collaboration with a healthcare company, we configured an automated directly-observed therapy (aDOT) platform for monitoring and supporting PrEP use. Based on interest expressed in focus groups among 54 YMSM, we combined aDOT with an electronic sexual diary to provide feedback on level of protection during sex and to motivate app use. In an 8-week optimization pilot with 20 YMSM in San Francisco and Atlanta, the app was found to be highly acceptable, with median System Usability Scale scores in the “excellent” range (80/100). App use was high, with median PrEP adherence of 91% based on aDOT-confirmed dosing. Most (84%) participants reported the app helped with taking PrEP. These promising findings support further evaluation of DOT Diary in future effectiveness studies.
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影响因子：
7.4
作者：
Ernsting C;Dombrowski SU;Oedekoven M;O Sullivan JL;Kanzler M;Kuhlmey A;Gellert P
通讯作者：
Gellert P
影响因子：
3.7
作者：
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影响因子：
12.7
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影响因子：
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作者：
Choopanya, Kachit;Martin, Michael;Vanichseni, Suphak
通讯作者：
Vanichseni, Suphak