L-Ascorbate biosynthesis in higher plants: the role of VTC2.
L-Ascorbate biosynthesis in higher plants: the role of VTC2.
复制标题
DOI:
10.1016/j.tplants.2008.08.005
复制
发表时间:
2008-11
影响因子:
20.5
通讯作者:
Clarke, Steven G.
中科院分区:
文献类型:
--
作者:
Linster, Carole L.;Clarke, Steven G.
In the past year, the last missing enzyme of the L-galactose pathway, the linear form of which appears to represent the major biosynthetic route to L-ascorbate (vitamin C) in higher plants, has been identified as a GDP-L-galactose phosphorylase. This enzyme catalyzes the first committed step in the synthesis of that vital antioxidant and enzyme cofactor. Here, we discuss how GDP-L-galactose phosphorylase enzymes, encoded in Arabidopsis by the paralogous VTC2 and VTC5 genes, function in concert with the other enzymes of the L-galactose pathway to provide plants the appropriate levels of L-ascorbate. We hypothesize that regulation of L-ascorbate biosynthesis might occur at more than one step and warrants further investigation to allow for the manipulation of vitamin C levels in plants.
登录
查看更多内容
影响因子:
7.2
作者:
Gatzek, S;Wheeler, GL;Smirnoff, N
通讯作者:
Smirnoff, N
DOI:
10.1073/pnas.96.7.4198
发表时间:
1999-03-30
影响因子:
11.1
作者:
Conklin, PL;Norris, SR;Last, RL
通讯作者:
Last, RL
DOI:
10.1073/pnas.93.18.9970
发表时间:
1996-09-03
影响因子:
11.1
作者:
Conklin, PL;Williams, EH;Last, RL
通讯作者:
Last, RL
影响因子:
6.5
作者:
Badejo, Adebanjo A.;Jeong, Seok T.;Esaka, Muneharu
通讯作者:
Esaka, Muneharu
影响因子:
4.3
作者:
Gao, Qjan;Zhang, Lixin
通讯作者:
Zhang, Lixin