Endogenous variation in ventromedial prefrontal cortex state dynamics during naturalistic viewing reflects affective experience.
Endogenous variation in ventromedial prefrontal cortex state dynamics during naturalistic viewing reflects affective experience.
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自然主义观察过程中腹侧前额叶皮层状态动力学的内源性变异反映了情感体验。
DOI：
10.1126/sciadv.abf7129
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发表时间：
2021-04
期刊：
影响因子：
13.6
通讯作者：
Manning JR
中科院分区：
文献类型：
--
作者：
Chang LJ;Jolly E;Cheong JH;Rapuano KM;Greenstein N;Chen PA;Manning JR
VMPFC归因于情感意义的经验，因为他们展开，并表现出独特的具体时空动态。我们如何处理正在进行的经验是由我们的个人历史，当前的需求和未来的目标塑造的。因此，参与处理这些主观评价的腹内侧前额叶皮层（vmPFC）活动似乎在个体之间具有高度特异性。为了阐明VMPFC在处理我们正在进行的经验中的作用，我们开发了一个计算框架和分析管道，以表征参与者观看45分钟电视剧时个体VMPFC响应的时空动态。通过功能磁共振成像，面部表情跟踪和自我报告的情感体验在四项研究中的结合，我们的数据表明，vmPFC缓慢地通过一系列离散状态，广泛映射到情感体验。虽然这些转变通常发生在人们的特殊时间，但参与者在节目中的高情感评价事件中表现出明显的状态一致性增加。我们的工作表明，vmPFC归因于情感意义，我们正在进行的经验。
The vmPFC ascribes affective meaning to experiences as they unfold and exhibits unique idiographic spatiotemporal dynamics. How we process ongoing experiences is shaped by our personal history, current needs, and future goals. Consequently, ventromedial prefrontal cortex (vmPFC) activity involved in processing these subjective appraisals appears to be highly idiosyncratic across individuals. To elucidate the role of the vmPFC in processing our ongoing experiences, we developed a computational framework and analysis pipeline to characterize the spatiotemporal dynamics of individual vmPFC responses as participants viewed a 45-minute television drama. Through a combination of functional magnetic resonance imaging, facial expression tracking, and self-reported emotional experiences across four studies, our data suggest that the vmPFC slowly transitions through a series of discretized states that broadly map onto affective experiences. Although these transitions typically occur at idiosyncratic times across people, participants exhibited a marked increase in state alignment during high affectively valenced events in the show. Our work suggests that the vmPFC ascribes affective meaning to our ongoing experiences.
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影响因子：
3.5
作者：
Abraham A;Pedregosa F;Eickenberg M;Gervais P;Mueller A;Kossaifi J;Gramfort A;Thirion B;Varoquaux G
通讯作者：
Varoquaux G
影响因子：
5.7
作者：
Chen G;Shin YW;Taylor PA;Glen DR;Reynolds RC;Israel RB;Cox RW
通讯作者：
Cox RW
影响因子：
25
作者：
Chikazoe, Junichi;Lee, Daniel H.;Kriegeskorte, Nikolaus;Anderson, Adam K.
通讯作者：
Anderson, Adam K.
影响因子：
5.2
作者：
Andrews-Hanna JR;Smallwood J;Spreng RN
通讯作者：
Spreng RN
DOI：
10.1523/jneurosci.1296-11.2011
发表时间：
2011-05-25
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Baria AT;Baliki MN;Parrish T;Apkarian AV
通讯作者：
Apkarian AV