The default network and self-generated thought: component processes, dynamic control, and clinical relevance.

The default network and self-generated thought: component processes, dynamic control, and clinical relevance.
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DOI:
10.1111/nyas.12360
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发表时间:
2014-05
影响因子:
5.2
通讯作者:
Spreng RN
Spreng RN
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Andrews-Hanna JR;Smallwood J;Spreng RN

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虽然自默认网络首次被强调为一个大规模的大脑系统以来,仅仅过去了十年,但近年来已经对网络的适应功能进行了深入研究。一个日益增长的主题强调了默认网络在内部指导或自我生成的思想中发挥着关键作用。在这里,我们综合了认知科学,神经科学和临床心理学的最新研究结果,将注意力集中在两个新兴的主题上,作为围绕默认网络的当前和未来方向。首先,我们提出的证据表明,自我生成的思想是一个多方面的结构,其组件的过程是由网络内的不同子系统的支持。其次,我们强调了默认网络的动态性,强调了它与执行控制系统的相互作用时,调节内部思想的各个方面。最后,我们讨论了网络的完整性中断的临床意义,并考虑当思想内容变得两极分化或网络互动变得中断或不平衡时的障碍。
Though only a decade has elapsed since the default network was first emphasized as being a large-scale brain system, recent years have brought great insight into the network’s adaptive functions. A growing theme highlights the default network as playing a key role in internally-directed—or self-generated—thought. Here, we synthesize recent findings from cognitive science, neuroscience, and clinical psychology to focus attention on two emerging topics as current and future directions surrounding the default network. First, we present evidence that self-generated thought is a multi-faceted construct whose component processes are supported by different subsystems within the network. Second, we highlight the dynamic nature of the default network, emphasizing its interaction with executive control systems when regulating aspects of internal thought. We conclude by discussing clinical implications of disruptions to the integrity of the network, and consider disorders when thought content becomes polarized or network interactions become disrupted or imbalanced.
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