Lung squamous cell carcinoma with solitary ocular metastasis and its successful treatment with thoracic surgery and chemotherapy: an interesting and rare case report.
Lung squamous cell carcinoma with solitary ocular metastasis and its successful treatment with thoracic surgery and chemotherapy: an interesting and rare case report.
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孤立性眼部转移的肺鳞状细胞癌及其通过胸外科手术和化疗的成功治疗：一个有趣且罕见的病例报告
DOI：
10.1186/s12885-018-4944-y
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发表时间：
2018-10-20
期刊：
影响因子：
3.8
通讯作者：
Ma K
中科院分区：
文献类型：
--
作者：
Guo Y;Wang X;Xiao J;Xu Y;Cai Y;Sun C;Ma K
据报道，肺癌眼转移的发生率为0.1- 7%，其中腺癌和小细胞肺癌占这些病例的最高比例。大多数病例涉及转移到除了眼睛以外的一个以上的其他远端器官。在这里，我们报告的第一次，肺鳞状细胞癌孤立症状眼转移的初始表现，是由多学科治疗（MDT）管理的情况下。一名妇女在医院眼科就诊，左眼疼痛和视力模糊1周。全身检查诊断为右下叶中央型肺癌伴眼部转移。在与包括外科、内科、眼科、放疗和影像科专家在内的MDT会诊后，患者接受了手术和化疗。她的眼部症状消失，眼部病变得到良好控制，没有任何特殊的眼部治疗。患者表现出延长的无进展生存期。这是首例以孤立性眼转移为首发表现的肺鳞状细胞癌罕见病例的报道。这位罕见的患者是基于循证医学进行治疗的，这表明了MDT内部合作的重要性。本病例的成功治疗为临床医生今后遇到类似病例提供了新的治疗参考。
The incidence of ocular metastasis from lung cancer is reported to be 0.1–7%, with adenocarcinoma and small cell lung cancer accounting for the highest proportions of these cases. The majority of cases involves metastasis to more than one other distal organ in addition to the eye. Here, we report for the first time, a case of lung squamous cell carcinoma with solitary symptomatic ocular metastasis as the initial manifestation that was managed by a multidisciplinary treatment (MDT). A woman presented at the ophthalmology department of hospital with a 1-week history of left eye pain and blurred vision. Systemic examination led to the diagnosis of central lung cancer in the right lower lobe with ocular metastasis. After consultations with an MDT, including specialists from the surgery, internal medicine, ophthalmology, radiotherapy and imaging departments, the patient underwent surgery and chemotherapy. Her eye symptoms disappeared, and the ocular lesion was well controlled without any specific ocular treatment. The patient demonstrated a prolonged progression-free survival. This is the first report of a rare case with solitary ocular metastasis as the initial manifestation of lung squamous cell carcinoma. This rare patient was treated based on evidence-based medicine, indicating the importance of cooperation within an MDT. The successful treatment of this case was reported as a new therapeutic reference for clinicians who encounter similar cases in the future.
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影响因子：
45.3
作者：
ALBAIN, KS;CROWLEY, JJ;LIVINGSTON, RB
通讯作者：
LIVINGSTON, RB
影响因子：
5.3
作者：
Lai, Chun-Liang;Fan, Kuo-Sheng;Fan, Wen-Hsiung
通讯作者：
Fan, Wen-Hsiung
影响因子：
13.7
作者：
Bechrakis, NE;Foerster, MH;Bornfeld, N
通讯作者：
Bornfeld, N
影响因子：
3.1
作者：
NYLEN, U;KOCK, E;WILKING, N
通讯作者：
WILKING, N
DOI：
10.1155/2013/213124
发表时间：
2013
期刊：
Case reports in ophthalmological medicine
影响因子：
--
作者：
Shimomura I;Tada Y;Miura G;Suzuki T;Matsumura T;Tsushima K;Terada J;Kurimoto R;Sakaida E;Sekine I;Takiguchi Y;Yamamoto S;Tatsumi K
通讯作者：
Tatsumi K