Characterization of soft polymers and gels using the pressure-bulge technique

Characterization of soft polymers and gels using the pressure-bulge technique
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使用压力膨胀技术表征软聚合物和凝胶

DOI:
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发表时间:
2008
期刊:
影响因子:
--
通讯作者:
W. Jackson
W. Jackson
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作者:
W. Jackson

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提出了一种利用压力膨胀技术表征模量在低MPa范围内的软质聚合物和水凝胶体相水合性质的方法。压力膨胀技术已被广泛用于薄膜的表征,特别是对于金属的情况。平面应变和圆形凸起技术的扩展,以确定的杨氏模量和泊松比的散装胶乳和硅橡胶片显示在这里,除了在时域中使用松弛试验的5%琼脂糖凝胶的粘弹性行为。 膜被夹在两个不锈钢板之间,这两个不锈钢板连接到液体压力室。连接到线性致动器的注射器引起压力和位移的变化,并且使用压力传感器和共焦位移传感器来真实的监测这些变化。提出的理论将测量的压力和位移数据转换为应力和拉伸数据,使用几何非线性分析,然后从该数据确定弹性/粘弹性性质。 膨胀试验的结果进行了比较,从单轴拉伸试验的数据对水合试样,和数据比较相对于每一个测试的材料显示出良好的协议之间的两个测量。这些结果表明,使用压力位移技术来表征其他软材料系统(包括生物聚合物和组织),以及在细胞基质的不同机械载荷条件下细胞与基质和细胞与细胞的相互作用,具有希望。
A method to characterize the bulk hydrated properties of soft polymers and hydrogels, whose moduli are in the low MPa regime, using the pressure-bulge technique is presented. The pressure-bulge technique has been used extensively in the characterization of thin films, particularly for the case of metals. The extension of the plane-strain and circular bulge techniques to determine the Young's modulus and Poisson's ratio of bulk latex and silicone rubber sheets are shown here, in addition to the viscoelastic behavior of 5% agarose gels in the time domain using relaxation tests. The membranes are clamped between two stainless steel plates that are connected to a liquid pressure chamber. A syringe connected to a linear actuator causes changes in the pressure and displacement, and a pressure sensor and confocal displacement sensor are used to monitor these changes in real time. The theory presented converts the measured pressure and displacement data into stress and stretch data, using a geometrically nonlinear analysis, and the elastic/viscoelastic properties are then determined from this data. The results from the bulge tests are compared with data from uniaxial tension tests on hydrated specimens, and the data comparison with respect to each of the materials tested show good agreement between the two measurements. These results show promise regarding the use of pressure-displacement techniques to characterize other soft material systems, including biological polymers and tissues, as well as cell-to-matrix and cell-to-cell interactions under varying mechanical loading conditions of cell substrates.
一种对培养细胞施加规定的同质菌株的系统。
DOI: 10.1152/jappl.2001.91.4.1600
发表时间: 2001
期刊: Journal of applied physiology (Bethesda, Md. : 1985)
影响因子: --
作者:
Waters,CM;Glucksberg,MR;Lautenschlager,EP;Lee,CW;VanMatre,RM;Warp,RJ;Savla,U;Healy,KE;Moran,B;Castner,DG;Bearinger,JP
通讯作者: Bearinger,JP
DOI: 10.1115/1.1797991
发表时间: 2004-10-01
影响因子: 1.7
作者:
Chen, QS;Suki, B;An, KN
通讯作者: An, KN