An innovative platform for treatment of vascular obstructions: System design and preliminary results
An innovative platform for treatment of vascular obstructions: System design and preliminary results
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治疗血管阻塞的创新平台：系统设计和初步结果
DOI：
10.1109/biorob.2012.6290758
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
A. Menciassi
中科院分区：
文献类型：
--
作者：
P. Miloro;M. Llewellyn;S. Tognarelli;G. Ciuti;E. Sinibaldi;P. Dario;A. Menciassi
对介入设备小型化的追求，以及外部手术平台和内部治疗工具之间的集成，不断推动着生物医学领域的研究。心血管系统的手术带来了巨大的挑战，但它也代表着高度靶向的治疗设备的选择性应用。在本文中，我们提出了一种治疗血管阻塞的机器人平台。它集成了基于磁拖动和超声波跟踪的移动和导航系统，涉及通过高强度聚焦超声对梗阻进行机械攻击的治疗模块，以及利用磁性纳米颗粒结合梗阻碎片并将其拖到安全区域进行清除的收集/检索模块。在这里，我们说明了系统概述和开发总体平台的技术和理论工具；报告了初步结果以及未来计划的工作，以证明所提出的方法的可行性。
The quest for miniaturization of interventional devices and the integration between external surgical platforms and internal therapeutic tools are continuously fostering research in the biomedical field. Operating in the cardiovascular system poses dramatic challenges, but it also represent the elective application for highly targeted therapeutic devices. In this paper we present a robotic platform for treating vascular obstructions. It integrates a system for locomotion and navigation based on magnetic dragging and ultrasound tracking, a therapeutic module which involves mechanical attack to the obstruction by means of high intensity focused ultrasound, and a collection/retrieval module exploiting magnetic nano-particles to bind the obstruction debris and to drag them to a safe region for removal. Here we illustrate the system overview and the technical and theoretical instruments for developing the overall platform; preliminary results, together with future planned works, are reported in order to demonstrate the feasibility of the proposed approach.
影响因子：
2.9
作者：
Maxwell, Adam D.;Cain, Charles A.;Duryea, Alexander P.;Yuan, Lingqian;Gurm, Hitinder S.;Xu, Zhen
通讯作者：
Xu, Zhen
DOI：
10.1016/j.jss.2010.10.039
发表时间：
2011-03
期刊：
The Journal of surgical research
影响因子：
--
作者：
Lukianova-Hleb EY;Koneva II;Oginsky AO;La Francesca S;Lapotko DO
通讯作者：
Lapotko DO