Differences between left- and right-sided neglect revisited: A large cohort study across multiple domains
Differences between left- and right-sided neglect revisited: A large cohort study across multiple domains
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重新审视左侧和右侧忽视之间的差异：跨多个领域的大型队列研究
DOI：
10.1080/13803395.2016.1262333
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发表时间：
2017
影响因子：
2.2
通讯作者：
T. Nijboer
中科院分区：
文献类型：
--
作者：
A. F. T. Brink;J. Verwer;Matthijs Biesbroek;J. Visser;T. Nijboer
摘要单侧空间忽略（USN）是一种可在左右半球损伤后发生的综合征。通常认为左侧的USN比右侧的USN更严重。在其他领域缺乏这种差异的证据。主要目的是比较左和右USN之间的频率、严重程度、区域特异性、认知、身体功能和身体独立性。次要目的是比较病变特征。共纳入335例住院康复的卒中患者。侧化注意缺陷的严重程度进行了测量与形状取消和线平分测试（在个人和个人以外的空间）和凯瑟琳Bergego量表。简易精神状态检查，Stichting Afasie Nederland评分，搜索组织（即，最佳R和交叉率），运动指数，平衡，移动性和自我护理进行了评估。对左侧、右侧和无USN患者的测量进行统计学比较。将病变重叠图与病变减影分析进行比较。结果：左侧超声心动图检出率（15.82%）高于右侧超声心动图检出率（9.25%）。两组的人口统计学和卒中特征相似。偏侧化注意缺陷在左侧USN中最为严重。在近个人和个人以外的空间中，USN在性质上更经常是左侧的。左侧USN的搜索效率较低。右USN的平衡较差。左侧和右侧USN之间的认知能力，沟通，运动强度，流动性和自我照顾没有差异。大多数左侧USN患者的右半球病变，而右侧USN患者的病变可能在左半球或右半球。总之，左和右USN都是常见的中风后。虽然偏侧注意力缺陷在左侧比在右侧USN中更严重，但在身体功能和身体独立性水平上的后果在很大程度上是可比的。从临床的角度来看，重要的是要有系统地筛选USN，无论是在右半球和左半球损伤后。
ABSTRACT Unilateral spatial neglect (USN) is a syndrome that can occur after right- and left-hemisphere damage. It is generally accepted that left-sided USN is more severe than right-sided USN. Evidence for such a difference in other domains is lacking. Primary aims were to compare frequency, severity, region specificity, cognition, physical functioning, and physical independence between left and right USN. Secondary aims were to compare lesion characteristics. A total of 335 stroke patients admitted for inpatient rehabilitation were included. The severity of the lateralized attentional deficit was measured with a shape cancellation and line bisection test (in peripersonal and extrapersonal space) and the Catherine Bergego scale. The Mini-Mental State Examination, Stichting Afasie Nederland score, search organization (i.e., best R and intersections rate), Motricity Index, balance, mobility, and self-care were assessed. Measures were statistically compared between left, right, and no USN patients. Lesion overlay plots were compared with lesion subtraction analyses. Results: Left USN (15.82%) was more frequent than right USN (9.25%). Demographic and stroke characteristics were comparable between groups. The lateralized attentional deficit was most severe in left USN. USN in both peripersonal and extrapersonal space was more frequently left-sided in nature. Search efficiency was lower in left USN. Balance was poorer in right USN. No differences between left and right USN were found for cognitive ability, communication, motor strength, mobility, and self-care. Most patients with left USN had right-hemispheric lesions, whereas patients with right USN could have lesions in either the left or the right hemisphere. To conclude, left and right USN are both common after stroke. Although the lateralized attention deficit is worse in left than in right USN, consequences at the level of physical functioning and physical independence are largely comparable. From a clinical perspective, it is important to systematically screen for USN, both after right- and after left-hemisphere damage.
影响因子：
13.9
作者：
Corbetta M;Shulman GL
通讯作者：
Shulman GL