Low Genetic Diversity and Strong Geographical Structure of the Critically Endangered White-Headed Langur (Trachypithecus leucocephalus) Inferred from Mitochondrial DNA Control Region Sequences.
Low Genetic Diversity and Strong Geographical Structure of the Critically Endangered White-Headed Langur (Trachypithecus leucocephalus) Inferred from Mitochondrial DNA Control Region Sequences.
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从线粒体 DNA 控制区序列推断，极危白头叶猴 (Trachypithecus leucocephalus) 的遗传多样性较低，地理结构较强。
DOI：
10.1371/journal.pone.0129782
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Yao M
中科院分区：
文献类型：
--
作者：
Wang W;Qiao Y;Pan W;Yao M
Many Asian colobine monkey species are suffering from habitat destruction and population size decline. There is a great need to understand their genetic diversity, population structure and demographic history for effective species conservation. The white-headed langur (Trachypithecus leucocephalus) is a Critically Endangered colobine species endemic to the limestone karst forests in southwestern China. We analyzed the mitochondrial DNA (mtDNA) control region sequences of 390 fecal samples from 40 social groups across the main distribution areas, which represented one-third of the total extant population. Only nine haplotypes and 10 polymorphic sites were identified, indicating remarkably low genetic diversity in the species. Using a subset of 77 samples from different individuals, we evaluated genetic variation, population structure, and population demographic history. We found very low values of haplotype diversity (h = 0.570 ± 0.056) and nucleotide diversity (π = 0.00323 ± 0.00044) in the hypervariable region I (HVRI) of the mtDNA control region. Distribution of haplotypes displayed marked geographical pattern, with one population (Chongzuo, CZ) showing a complete lack of genetic diversity (having only one haplotype), whereas the other population (Fusui, FS) having all nine haplotypes. We detected strong population genetic structure among habit patches (Φ ST = 0.375, P < 0.001). In addition, the Mantel test showed a significant correlation between the pairwise genetic distances and geographical distances among social groups in FS (correlation coefficient = 0.267, P = 0.003), indicting isolation-by-distance pattern of genetic divergence in the mtDNA sequences. Analyses of demographic history suggested an overall stable historical population size and modest population expansion in the last 2,000 years. Our results indicate different genetic diversity and possibly distinct population history for different local populations, and suggest that CZ and FS should be considered as one evolutionarily significant unit (ESU) and two management units (MUs) pending further investigation using nuclear markers.
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影响因子：
3.7
作者：
Chaves PB;Alvarenga CS;Possamai Cde B;Dias LG;Boubli JP;Strier KB;Mendes SL;Fagundes V
通讯作者：
Fagundes V
影响因子：
5.9
作者：
Huang, CM;Wei, FW;Li, HH
通讯作者：
Li, HH
影响因子：
14.9
作者：
DEUTER, R;PEITSCH, S;MULLER, O
通讯作者：
MULLER, O
影响因子：
2.4
作者：
Jin, Tong;Wang, De-Zhi;Pan, Wen-Shi
通讯作者：
Pan, Wen-Shi
影响因子：
1.7
作者：
Kanthaswamy, Sreetharan;Kurushima, Jennifer D.;Smith, David Glenn
通讯作者：
Smith, David Glenn