The molecular biology of nairoviruses, an emerging group of tick-borne arboviruses.
The molecular biology of nairoviruses, an emerging group of tick-borne arboviruses.
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DOI：
10.1007/s00705-013-1940-z
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发表时间：
2014-06
影响因子：
2.7
通讯作者：
Baron MD
中科院分区：
文献类型：
--
作者：
Lasecka L;Baron MD
内罗病毒是一组迅速出现的蜱传布尼亚病毒，包括人类病原体（克里米亚-刚果出血热病毒[CCHFV]）和牲畜病原体（内罗毕羊病病毒[NSDV]，也称为Ganjam病毒），以及大量尚未建立正常脊椎动物宿主的病毒。对这组病毒的研究相当有限，尤其是因为CCHFV是BSL 4人类病原体，限制了能够研究活病毒的实验室数量，而NSDV虽然在幼稚动物中具有高致病性，但在发达国家并不被视为威胁，使其成为低优先级。然而，近年来已经看到了显着的进展，我们对这些病毒的生物学，特别是CCHFV的理解，这篇文章试图把我们现有的知识，以产生一个整体的图片，他们的分子生物学，强调特别是无知的未来研究领域。
The nairoviruses are a rapidly emerging group of tick-borne bunyaviruses that includes pathogens of humans (Crimean-Congo hemorrhagic fever virus [CCHFV]) and livestock (Nairobi sheep disease virus [NSDV], also known as Ganjam virus), as well as a large number of viruses for which the normal vertebrate host has not been established. Studies on this group of viruses have been fairly limited, not least because CCHFV is a BSL4 human pathogen, restricting the number of labs able to study the live virus, while NSDV, although highly pathogenic in naive animals, is not seen as a threat in developed countries, making it a low priority. Nevertheless, recent years have seen significant progress in our understanding of the biology of these viruses, particularly that of CCHFV, and this article seeks to draw together our existing knowledge to generate an overall picture of their molecular biology, underlining areas of particular ignorance for future studies.
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DOI：
10.4269/ajtmh.1980.29.941
发表时间：
1980-01-01
影响因子：
3.3
作者：
BURNEY, MI;GHAFOOR, A;CASALS, J
通讯作者：
CASALS, J
影响因子：
14.9
作者：
Ariza A;Tanner SJ;Walter CT;Dent KC;Shepherd DA;Wu W;Matthews SV;Hiscox JA;Green TJ;Luo M;Elliott RM;Fooks AR;Ashcroft AE;Stonehouse NJ;Ranson NA;Barr JN;Edwards TA
通讯作者：
Edwards TA
影响因子：
5.4
作者：
Billecocq, A;Spiegel, M;Haller, O
通讯作者：
Haller, O
影响因子：
5.4
作者：
Bergeron, Eric;Vincent, Martin J.;Nichol, Stuart T.
通讯作者：
Nichol, Stuart T.
影响因子：
3.7
作者：
Bridgen, A;Dalrymple, DA;Elliott, RM
通讯作者：
Elliott, RM