Trabeculectomy is associated with retrobulbar hemodynamic changes. A color Doppler analysis.
Trabeculectomy is associated with retrobulbar hemodynamic changes. A color Doppler analysis.
复制标题
小梁切除术与球后血流动力学变化相关。
DOI：
10.1016/s0161-6420(13)31332-3
复制
发表时间：
1994
期刊：
影响因子：
13.7
通讯作者：
C. Schmidt
中科院分区：
文献类型：
--
作者：
J. R. Trible;R. Sergott;G. L. Spaeth;Richard P. Wilson;L. Jay Katz;Marlene R. Moster;C. Schmidt
目的：确定彩色多普勒血流动力学变化是否发生在球后循环后trabeculectomy.Methods：作者前瞻性纳入20例接受小梁切除术，并进行彩色多普勒成像的双眼术前，然后在大约2，5，14周的时间间隔后手术。测定视网膜中央动脉、鼻侧和颞侧睫状后短动脉和眼动脉的收缩期最大流速、平均流速、舒张末期流速和血管阻力（阻力指数）。使用配对Student'sttest对手术眼和非手术眼的术前和术后测量值进行统计比较。结果：观察到平均和舒张末期速度在统计学上显着增加，视网膜中央动脉和两条短血管的血管阻力显着降低睫状后动脉在几乎所有术后间隔（25/27例术前和术后比较; P< 0.05）眼动脉在所有时间段均显示流速增加，平均血流速度术后3个间期中仅1个间期和舒张末期血流速度术后3个间期中仅2个间期有统计学显著性增加（P< 0.05）。耐药性无明显变化。在任何时间间隔，非手术眼的视网膜中央动脉或鼻或颞睫状后短动脉的流速或阻力均未显示出统计学显著变化（27例术前和术后平均流速、舒张末期流速和阻力指数比较中0例）。结论：慢性青光眼患者小梁切除术后，视网膜中央动脉和短后动脉的平均血流速度和舒张末期血流速度持续增加，阻力指数下降，眼压降低。这些发现与通过这些血管的血流增加一致，但不能诊断。
Purpose:To determine whether color Doppler hemodynamic changes occur in the retrobulbar circulation after trabeculectomy.Methods:The authors prospectively enrolled 20 patients undergoing trabeculectomy and performed color Doppler imaging of both eyes before surgery and then at approximately 2-, 5-, and 14-week intervals after surgery. The systolic maximum velocity, mean velocity, end-diastolic velocity, and vascular resistance (resistance index) of the central retinal artery, nasal and temporal short posterior ciliary arteries, and ophthalmic arteries were determined. Statistical comparison of the preoperative and postoperative measures were performed on both the operative and nonoperative eye using the paired Student'sttest.Results:A statistically significant increase was observed in the mean and enddiastolic velocity and a significant decrease in the vascular resistance of the central retinal artery and both short posterior ciliary arteries at nearly all postoperative intervals (25 of 27 preoperative and postoperative comparisons;P< 0.05) The ophthalmic artery, while showing an increased velocity at all intervals, only attained a statistically significant increase in one of three postoperative intervals for mean velocity and two of three intervals for end-diastolic velocity (P< 0.05). There were no notable changes in resistance. The nonoperative eye did not show a statistically significant change in velocity or in resistance in the central retinal artery or either nasal or temporal short posterior ciliary artery at any interval (0 of 27 preoperative and postoperative comparisons for mean velocity, end-diastolic velocity, and resistance index.)Conclusion:Sustained increases in mean velocity and end-diastolic velocity and decreases in resistance index were observed in the central retinal artery and the short posterior arteries with clinically attainable reductions in intraocular pressure after trabeculectomy in patients with chronic glaucoma. These findings are consistent with, but not diagnostic of, increased blood flow through these vessels.
影响因子：
13.7
作者：
J. Grunwald;C. E. Riva;Richard A. Stone;Edwin U. Keates;B. Petrig
通讯作者：
J. Grunwald;C. E. Riva;Richard A. Stone;Edwin U. Keates;B. Petrig
激光多普勒测量人体视神经乳头的相对血流速度。
影响因子：
4.4
作者：
Riva,CE;Grunwald,JE;Sinclair,SH
通讯作者：
Sinclair,SH