Are symptom features of depression during pregnancy, the postpartum period and outside the peripartum period distinct? Results from a nationally representative sample using item response theory (IRT).

Are symptom features of depression during pregnancy, the postpartum period and outside the peripartum period distinct? Results from a nationally representative sample using item response theory (IRT).
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DOI:
10.1002/da.22334
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发表时间:
2015-02
影响因子:
7.4
通讯作者:
Blanco, Carlos
Blanco, Carlos
中科院分区:
医学1区
文献类型:
--
作者:
Hoertel, Nicolas;Lopez, Saioa;Peyre, Hugo;Wall, Melanie M.;Gonzalez-Pinto, Ana;Limosin, Frederic;Blanco, Carlos

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在怀孕期间、产后期间和这些期间以外的抑郁症状表达是否存在系统性差异(即,在月经周期之外)仍然存在争议。本研究的目的是使用基于项目反应理论(IRT)的方法,在将抑郁严重程度等同后,检查育龄妇女报告DSM-IV抑郁发作(MDE)症状的可能性差异(即,年龄在18-50岁之间的妇女在怀孕期间、产后期间和围产期以外。我们使用来自美国的育龄妇女(n = 11,256)的大型全国代表性样本进行了这些分析,这些妇女参加了第二波全国酒精和相关疾病流行病学调查(NESARC)。所有抑郁标准的12个月总体患病率(除了无意识/内疚)在围产期外,孕妇显着低于育龄妇女,而所有症状的患病率(除了“精神症状”)在产后和非围产期组之间没有显着差异。当等同于抑郁严重程度时,妊娠状态对MDE症状的认可率没有临床显著差异。这项研究表明,育龄妇女抑郁症状的临床表现在怀孕期间,产后期间和围产期外没有什么不同。这些研究结果并没有提供心理测量学的支持,包括围产期发作的说明符在DSM-5的重性抑郁症。
Whether there are systematic differences in depression symptom expression during pregnancy, the postpartum period and outside these periods (i.e., outside the peripartum period) remains debated. The aim of this study was to use methods based on item response theory (IRT) to examine, after equating for depression severity, differences in the likelihood of reporting DSM-IV symptoms of major depressive episode (MDE) in women of childbearing age (i.e., aged 18-50) during pregnancy, the postpartum period and outside the peripartum period. We conducted these analyses using a large, nationally representative sample of women of childbearing age from the USA (n = 11,256) who participated in the second wave of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). The overall 12-month prevalence of all depressive criteria (except for worthlessness/guilt) was significantly lower in pregnant women than in women of childbearing age outside the peripartum period, whereas the prevalence of all symptoms (except for “psychomotor symptoms”) were not significantly different between the postpartum and the non-peripartum group. There were no clinically significant differences in the endorsement rates of symptoms of MDE by pregnancy status when equating for levels of depression severity. This study suggests that the clinical presentation of depressive symptoms in women of childbearing age does not differ during pregnancy, the postpartum period and outside the peripartum period. These findings do not provide psychometric support for the inclusion of the peripartum onset specifier for major depressive disorder in the DSM-5.
DOI: 10.15288/jsa.1999.60.790
发表时间: 1999-11-01
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