Ethnic differences in the effects of the DASH diet on nocturnal blood pressure dipping in individuals with high blood pressure.
Ethnic differences in the effects of the DASH diet on nocturnal blood pressure dipping in individuals with high blood pressure.
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DOI：
10.1038/ajh.2011.152
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发表时间：
2011-12
影响因子：
3.2
通讯作者：
Sherwood, Andrew
中科院分区：
文献类型：
--
作者：
Prather, Aric A.;Blumenthal, James A.;Hinderliter, Alan L.;Sherwood, Andrew
在非裔美国人中，夜间血压(BP)下降的种族差异可能是增加不良心血管事件风险的原因之一。DASH(停止高血压的饮食方法)饮食已被证明在降低临床和动态血压方面有效；然而，DASH饮食对血压下降的影响尚不清楚。118名临床血压较高(收缩压130~159；舒张压85~99)及理想体重以上的男性和女性被随机分为两组，一组为DASH饮食干预组，另一组为普通饮食对照组。在基线和4个月干预期结束时测量24小时动态血压。在基线时，与高加索人(n=75)相比，AAS(n=43)的夜间SBP下降不明显，而且更有可能被归类为非勺型(夜间SBP下降10%，AAS：51%对CAS：27%)。随机配对DASH饮食干预后，UC患者的SBP下降较AAS明显改善(P=0.04)，而CAS患者的SBP下降无明显变化(P=0.72)。干预后，SBP下降的种族差异不再有统计学意义(非勺型：AAS：44%对CAS：32%；P=0.19)。我们的研究提供了初步证据，表明在超重的男性和患有高血压的女性中，AAS特别可能受益于与DASH饮食相关的增加的SBP下降。
Ethnic differences in nocturnal blood pressure (BP) dipping may contribute to the increased risk for adverse cardiovascular events noted in African Americans (AAs). The DASH (Dietary Approaches to Stop Hypertension) diet has been shown to be efficacious in lowering clinic and ambulatory BP; however, the effect of the DASH diet on BP dipping is unclear. One hundred and eighteen men and women with high clinic BP (systolic BP (SBP) 130–159; diastolic BP 85–99) and above ideal body weight were randomized to a DASH diet intervention or to a usual diet control (UC) condition. Measures of 24-h ambulatory BP were obtained at baseline and at the end of the 4-month intervention period. At baseline, AAs (n = 43) displayed blunted nocturnal SBP dipping compared to Caucasians (CAs; n = 75) and were more likely to be categorized as nondippers (<10% nocturnal decline in SBP, AAs: 51% vs. CAs: 27%). AAs randomized to the DASH diet intervention showed a significant improvement in SBP dipping postintervention compared to AAs in the UC condition (P = 0.04), whereas there was no appreciable change in SBP dipping in CAs (P = 0.72). Following the intervention, ethnic differences in SBP dipping were no longer statistically significant (nondipper status: AAs: 44% vs. CAs: 32%; P = 0.19). Our study provides preliminary evidence suggesting that in overweight men and women with high BP, AAs may be especially likely to benefit from augmented SBP dipping associated with consumption of the DASH diet.
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影响因子：
8.3
作者：
Profant, J;Dimsdale, JE
通讯作者：
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影响因子：
3.2
作者：
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DOI：
10.2165/00129784-200505010-00001
发表时间：
2005-01-01
期刊：
American journal of cardiovascular drugs : drugs, devices, and other interventions
影响因子：
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作者：
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通讯作者：
Douglas, Janice G
影响因子：
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作者：
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通讯作者：
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