Post-Stroke Brain Health Monitoring and Optimization: A Narrative Review.

Post-Stroke Brain Health Monitoring and Optimization: A Narrative Review.
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DOI:
10.3390/jcm12237413
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发表时间:
2023-11-29
影响因子:
3.9
通讯作者:
--
中科院分区:
医学2区
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--
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近年来,在卒中的急性治疗和二级预防方面取得了重大进展。然而,很大一部分中风幸存者将继续有持久的身体,认知和心理残疾,从次优中风后的大脑健康。因此,中风后大脑健康受损需要临床医生和研究人员的更多关注。在这篇基于PubMed、Scopus和Web of Science数据库的开放时间框架搜索的叙述性综述中,我们定义了卒中后脑健康,并评估了专注于可改变的血管、生活方式和心理社会因素以优化卒中后脑健康的研究。此外,我们提出了在主要的卒中后过渡点监测和管理卒中后脑健康的临床建议,这些过渡点集中在四个关键的相互交织的领域:认知,心理社会健康,身体功能和全球血管健康。最后,我们讨论了中风后脑健康领域未来可能的工作,包括使用远程监测和干预,神经调节,多发病干预,丰富的环境,以及需要解决中风后脑健康的不平等。由于卒中后脑健康是一个相对较新的、快速发展的、广泛的临床和研究领域,本综述旨在识别和总结证据基础,以帮助临床医生和研究人员定制自己的方法,将卒中后脑健康融入他们的实践中。
Significant advancements have been made in recent years in the acute treatment and secondary prevention of stroke. However, a large proportion of stroke survivors will go on to have enduring physical, cognitive, and psychological disabilities from suboptimal post-stroke brain health. Impaired brain health following stroke thus warrants increased attention from clinicians and researchers alike. In this narrative review based on an open timeframe search of the PubMed, Scopus, and Web of Science databases, we define post-stroke brain health and appraise the body of research focused on modifiable vascular, lifestyle, and psychosocial factors for optimizing post-stroke brain health. In addition, we make clinical recommendations for the monitoring and management of post-stroke brain health at major post-stroke transition points centered on four key intertwined domains: cognition, psychosocial health, physical functioning, and global vascular health. Finally, we discuss potential future work in the field of post-stroke brain health, including the use of remote monitoring and interventions, neuromodulation, multi-morbidity interventions, enriched environments, and the need to address inequities in post-stroke brain health. As post-stroke brain health is a relatively new, rapidly evolving, and broad clinical and research field, this narrative review aims to identify and summarize the evidence base to help clinicians and researchers tailor their own approach to integrating post-stroke brain health into their practices.
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