Forensic application and genetic diversity of 21 autosomal STR loci in five major population groups of Pakistan
Forensic application and genetic diversity of 21 autosomal STR loci in five major population groups of Pakistan
复制标题
巴基斯坦5个主要人群21个常染色体STR基因座的法医学应用和遗传多样性
DOI：
10.1007/s00414-020-02393-y
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发表时间：
2020
影响因子：
2.1
通讯作者：
N. Morling
中科院分区：
文献类型：
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作者：
Muhammad Adnan Shan;C. Børsting;N. Morling
GlobalFilerTM PCR扩增试剂盒中包含的21个常染色体STR基因座的遗传多样性调查，529名巴基斯坦人属于旁遮普人，普什图人，信德人，Saraiki和Baloch种族群体。群体遗传参数和法医学信息的指标进行了评估。SE 33在所有研究人群中显示出最大的歧视能力。组合匹配概率范围为8.06E−27（Saraiki）至1.05E−26（Baloch），组合排除能力范围为0.9999999902（Punjabi）至0.9999999964（Pashtun）。Baloch群体中的D12 S391和Saraiki群体中的D2 S441偏离Hardy-Weinberg平衡。显着的遗传距离之间观察到旁遮普，普什图，俾路支人口。这项研究支持利用GlobalFilerTM STR试剂盒在巴基斯坦的法医应用。
Investigation of genetic diversity of the 21 autosomal STR loci included in the GlobalFilerTM PCR Amplification Kit in 529 Pakistani individuals belonging to the Punjabi, Pashtun, Sindhi, Saraiki, and Baloch ethnic groups. Population genetic parameters and forensic informative metrics for each group were evaluated. SE33 showed the greatest power of discrimination in all populations studied. The combined match probability ranged from 8.06E−27 (Saraiki) to 1.05E−26 (Baloch), and the combined power of exclusion ranged from 0.99999999902 (Punjabi) to 0.99999999964 (Pashtun). D12S391 in the Baloch population and D2S441 in the Saraiki population showed deviation from Hardy-Weinberg equilibrium. Significant genetic distances were observed between the Punjabi, Pashtun, and Baloch populations. This study supports the utilization of the GlobalFilerTM STR kit for forensic applications in Pakistan.
巴基斯坦 YAP Y 染色体的非洲和黎凡特起源。
影响因子：
--
作者：
Qamar,R;Ayub,Q;Khaliq,S;Mansoor,A;Karafet,T;Mehdi,SQ;Hammer,MF
通讯作者：
Hammer,MF
影响因子：
10.7
作者：
Takezaki, Naoko;Nei, Masatoshi;Tamura, Koichiro
通讯作者：
Tamura, Koichiro