New data identify an increasing sex ratio of multiple sclerosis in Sweden.
New data identify an increasing sex ratio of multiple sclerosis in Sweden.
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DOI：
10.1177/1352458514530021
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发表时间：
2014-10
期刊：
影响因子：
--
通讯作者：
Hillert J
中科院分区：
文献类型：
--
作者：
Westerlind H;Boström I;Stawiarz L;Landtblom AM;Almqvist C;Hillert J
An increasing women-to-men ratio in later birth cohorts of patients with multiple sclerosis (MS) has been observed in several populations and has been hypothesised to be due to one or several environmental factors of importance for disease aetiology. However, in a study based on data from the Swedish MS registry (SMSreg) this ratio was recently reported to be rather stable during the 20th century. The purpose of this study was to reinvestigate the women-to-men ratio in Sweden based on data from all available data sources, including deceased patients. We combined data from the SMSreg with data from national patient registers. In total we obtained information on 19,510 MS patients born 1931–1985, 13,321 women and 6189 men. The women-to-men ratio increased from 1.70 for patients born in the 1930s to 2.67 for patients born in the 1980s. When comparing the coverage of SMSreg to the full data set, a significantly higher proportion of women born 1931–1935 compared to men born in the same period were found in SMSreg, resulting in a sampling bias hiding the increasing sex ratio in the full material. The women-to-men ratio in MS has increased in Sweden during the 20th century similarly to observations in other western countries.
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影响因子：
5.7
作者：
SCHOENBERG B S
通讯作者：
SCHOENBERG B S
影响因子：
6
作者：
Kampman, Margitta T.;Aarseth, Jan Harald;Torkildsen, Oivind
通讯作者：
Torkildsen, Oivind
影响因子：
3.7
作者：
Trojano M;Lucchese G;Graziano G;Taylor BV;Simpson S Jr;Lepore V;Grand'maison F;Duquette P;Izquierdo G;Grammond P;Amato MP;Bergamaschi R;Giuliani G;Boz C;Hupperts R;Van Pesch V;Lechner-Scott J;Cristiano E;Fiol M;Oreja-Guevara C;Saladino ML;Verheul F;Slee M;Paolicelli D;Tortorella C;D'Onghia M;Iaffaldano P;Direnzo V;Butzkueven H;MSBase Study Group and the New Zealand MS Prevalence Study Group
通讯作者：
MSBase Study Group and the New Zealand MS Prevalence Study Group
影响因子：
48
作者：
Orton, Sarah-Michelle;Herrera, Blanca M.;Ebers, George C.
通讯作者：
Ebers, George C.
影响因子：
5.1
作者：
Ramagopalan, S. V.;Byrnes, J. K.;Sadovnick, A. D.
通讯作者：
Sadovnick, A. D.