Sparse incomplete representations: a potential role of olfactory granule cells.
Sparse incomplete representations: a potential role of olfactory granule cells.
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DOI:
10.1016/j.neuron.2011.07.031
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发表时间:
2011-10-06
期刊:
影响因子:
16.2
通讯作者:
Rinberg D
中科院分区:
文献类型:
--
作者:
Koulakov AA;Rinberg D
Mitral/tufted cells of the olfactory bulb receive odorant information from receptor neurons and transmit this information to the cortex. Studies in awake behaving animals have found that sustained responses of mitral cells to odorants are rare, suggesting sparse combinatorial representation of the odorants. Careful alignment of mitral cell firing with the phase of the respiration cycle revealed brief transient activity in the larger population of mitral cells, which respond to odorants during a small fraction of the respiration cycle. Responses of these cells are therefore temporally sparse. Here, we propose a mathematical model for the olfactory bulb network that can reproduce both combinatorially and temporally sparse mitral cell codes. We argue that sparse codes emerge as a result of the balance between mitral cells' excitatory inputs and inhibition provided by the granule cells. Our model suggests functional significance for the dendrodendritic synapses mediating interactions between mitral and granule cells.
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影响因子:
16.2
作者:
Abraham NM;Egger V;Shimshek DR;Renden R;Fukunaga I;Sprengel R;Seeburg PH;Klugmann M;Margrie TW;Schaefer AT;Kuner T
通讯作者:
Kuner T
影响因子:
64.8
作者:
HOPFIELD, JJ
通讯作者:
HOPFIELD, JJ
DOI:
10.1016/0013-4694(50)90075-7
发表时间:
1950-01-01
期刊:
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子:
--
作者:
ADRIAN, ED
通讯作者:
ADRIAN, ED
影响因子:
64.8
作者:
Olshausen, BA;Field, DJ
通讯作者:
Field, DJ
影响因子:
2.5
作者:
Fuentes, Romulo A.;Aguilar, Marcelo I.;Maldonado, Pedro E.
通讯作者:
Maldonado, Pedro E.