PRESIDENTIAL ADDRESS* SEX AND SCHISTOSOMES: AN INTERESTING BIOLOGICAL INTERPLAY WITH CONTROL IMPLICATIONS
PRESIDENTIAL ADDRESS* SEX AND SCHISTOSOMES: AN INTERESTING BIOLOGICAL INTERPLAY WITH CONTROL IMPLICATIONS
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总统讲话* 性与血吸虫：具有控制意义的有趣的生物相互作用
作者：
P. LoVerde
血吸虫寄生虫是具有复杂生命周期的多细胞真核生物。成对蠕虫产生的卵期在寄生虫的传播中很重要，并对致病负责。对于1种，曼氏血吸虫，雌虫每天产生大约300个卵(Moore和Sandrain，1956)。卵由雌性血吸虫沉积后，会引发肉芽肿炎症反应(Damian，1987)。大约一半的沉淀卵通过肠壁进入外部环境，并被排泄物排出，继续生命周期。其余50%在循环中被卷走，并在肝门静脉周围滤出，导致门脉周围纤维化、门脉高压和肠道血吸虫病的严重后遗症，如肝脾肿大、食道和胃底静脉曲张。
Schistosome parasites are muticellular eucaryotic organisms that have a complex life cycle. The egg stage produced by the worm pairs is important in transmission of the parasite and responsible for pathogenesis. For 1 species, Schistosoma mansoni, the female worm produces approximately 300 eggs per day (Moore and Sandground, 1956). The eggs, after they are deposited by the female schistosome, incite a granulomatous inflammatory reaction (Damian, 1987). Approximately half of the deposited eggs reach the outside environment by passing through the wall of the intestine and being voided with excreta, to continue the life cycle. The other 50% are swept up in the circulation and filter out in the periportal tracts of the liver, resulting in periportal fibrosis, portal hypertension, and the serious sequelae of intestinal schistosomiasis such as hepatosplenomegaly and esophageal and gastric varicies.
影响因子：
4.6
作者：
A. Oro;M. Mckeown;R. Evans
通讯作者：
A. Oro;M. Mckeown;R. Evans
曼氏血吸虫 Ras 同源物的表征。
影响因子：
1.5
作者：
Osman,A;Niles,EG;LoVerde,PT
通讯作者：
LoVerde,PT
曼氏血吸虫 PUR-α 家族成员的鉴定和功能表征。
影响因子：
1.5
作者：
Fantappie,MR;Osman,A;Niles,EG;LoVerde,PT
通讯作者：
LoVerde,PT