The feasibility of a "no tube, no fasting" fast-track recovery protocol after esophagectomy for esophageal cancer patients aged 75 and over.
The feasibility of a "no tube, no fasting" fast-track recovery protocol after esophagectomy for esophageal cancer patients aged 75 and over.
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DOI：
10.3389/fonc.2023.1144047
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发表时间：
2023
影响因子：
4.7
通讯作者：
中科院分区：
文献类型：
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对于≥75岁的老年食道癌患者，手术治疗是否安全有效，使用相对激进的“不插管，不禁食”的快速康复方案是否可行仍是争论的话题。我们对这两个问题进行了回顾分析。我们回顾性收集了2015年4月至2017年12月在本院胸外科内科1号病房行McKeown微创食道切除术(MIE)联合早期口服喂养(EOF)术后第1天的患者资料。观察术前特点、术后并发症、手术时间、术中出血量、吻合口漏持续时间、住院时间和存活率。23例老年食道癌患者接受了EOF手术。两组术中措施无明显差异。术后并发症发生率为34.8%(8/23)。2例患者(8.7%)在EOF可行性分析期间提前终止。23例患者平均住院11.4天(5-42天)，中位生存期51个月。≥75岁以上可切除食道癌患者，通过积极手术治疗，可获得长期生存。而且，对于老年患者来说，不插管、不禁食的快速康复方案是安全可行的。
For elderly patients aged ≥75 with esophageal cancer, whether surgical treatment is safe and effective and whether it is feasible to use a relatively radical “no tube, no fasting” fast-track recovery protocol remain topics of debate. We conducted a retrospective analysis to shed light on these two questions. We retrospectively collected the data of patients who underwent McKeown minimally invasive esophagectomy (MIE) combined with early oral feeding (EOF) on postoperative day 1 between April 2015 and December 2017 at Medical Group 1, Ward 1, Department of Thoracic Surgery of our hospital. Preoperative characteristics, postoperative complications, operation time, intraoperative blood loss, duration of anastomotic leakage (day), hospital stay, and survival were evaluated. Twenty-three elderly patients with esophageal cancer underwent surgery with EOF. No significant difference was observed in intraoperative measures. The incidence of postoperative complications was 34.8% (8/23). Two patients (8.7%) were terminated early during the analysis of the feasibility of EOF. For all 23 patients, the mean hospital stay was 11.4 (5-42) days, and the median survival was 51 months. Patients aged ≥75 with resectable esophageal cancer can achieve long-term survival with active surgical treatment. Moreover, the “no tube, no fasting” fast-track recovery protocol is safe and feasible for elderly patients.
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影响因子：
5.2
作者：
Mantziari S;Teixeira Farinha H;Bouygues V;Vignal JC;Deswysen Y;Demartines N;Schäfer M;Piessen G
通讯作者：
Piessen G
DOI：
10.1016/s0140-6736(17)33326-3
发表时间：
2018-03-17
期刊：
Lancet (London, England)
影响因子：
--
作者：
Allemani C;Matsuda T;Di Carlo V;Harewood R;Matz M;Nikšić M;Bonaventure A;Valkov M;Johnson CJ;Estève J;Ogunbiyi OJ;Azevedo E Silva G;Chen WQ;Eser S;Engholm G;Stiller CA;Monnereau A;Woods RR;Visser O;Lim GH;Aitken J;Weir HK;Coleman MP;CONCORD Working Group
通讯作者：
CONCORD Working Group
影响因子：
2.2
作者：
Schlottmann, Francisco;Strassle, Paula D.;Patti, Marco G.
通讯作者：
Patti, Marco G.
影响因子：
9
作者：
Sun, Hai-Bo;Li, Yin;Chang, Andrew C.
通讯作者：
Chang, Andrew C.
影响因子：
3.4
作者：
Zhu, Zhengshuai;Li, Yin;Liu, Qi
通讯作者：
Liu, Qi