A modified two-process Knox test for investigating the relationship between law enforcement opioid seizures and overdoses
A modified two-process Knox test for investigating the relationship between law enforcement opioid seizures and overdoses
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改进的两过程诺克斯测试,用于调查执法阿片类药物缉获和过量之间的关系
DOI:
10.1098/rspa.2021.0195
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发表时间:
2021
期刊:
影响因子:
--
通讯作者:
Flaxman, S.
中科院分区:
文献类型:
--
作者:
Mohler, G.;Mishra, S.;Ray, B.;Magee, L.;Huynh, P.;Canada, M.;O’Donnell, D.;Flaxman, S.
Recent research has shown an association between monthly law enforcement drug seizure events and accidental drug overdose deaths using cross-sectional data in a single state, whereby increased seizures correlated with more deaths. In this study, we conduct statistical analysis of street-level data on law enforcement drug seizures, along with street-level data on fatal and non-fatal overdose events, to determine possible micro-level causal associations between opioid-related drug seizures and overdoses. For this purpose, we introduce a novel, modified two-process Knox test that controls for self-excitation to measure clustering of overdoses nearby in space and time following law enforcement seizures. We observe a small, but statistically significant (p< 0.001), effect of 17.7 excess non-fatal overdoses per 1000 law enforcement seizures within three weeks and 250 m of a seizure. We discuss the potential causal mechanism for this association along with policy implications.
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影响因子:
4.4
作者:
Amlani A;McKee G;Khamis N;Raghukumar G;Tsang E;Buxton JA
通讯作者:
Buxton JA
影响因子:
1.9
作者:
S. Flaxman;Daniel B. Neill;Alex Smola
通讯作者:
Alex Smola
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
Brian R. Wyant;Ralph B. Taylor;J. Ratcliffe;Jennifer D. Wood
通讯作者:
Jennifer D. Wood
影响因子:
4.2
作者:
Hayashi K;Milloy MJ;Lysyshyn M;DeBeck K;Nosova E;Wood E;Kerr T
通讯作者:
Kerr T
DOI:
--
发表时间:
2003
期刊:
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.
影响因子:
--
作者:
Wood,Evan;Tyndall,MarkW;Spittal,PatriciaM;Li,Kathy;Anis,AslamH;Hogg,RobertS;Montaner,JulioSG;O'Shaughnessy,MichaelV;Schechter,MartinT
通讯作者:
Schechter,MartinT